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Which one of the following DNA viruses replicates in the cytoplasm rather than the nucleus?

  • A.Adenovirus
  • B.Herpes simplex virus
  • C.Papillomavirus
  • D.Poxvirus

Answer: D

Poxviruses are the exception among DNA viruses: they replicate entirely in the cytoplasm and therefore carry the enzymes they need, including their own transcriptase, rather than borrowing nuclear machinery. All the other families listed replicate in the nucleus.

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