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Prions differ fundamentally from viruses because they

  • A.are enveloped in host lipid
  • B.replicate only in the nucleus
  • C.contain no nucleic acid
  • D.have a segmented RNA genome

Answer: C

A prion is a misfolded protein that propagates its abnormal conformation to the normal form of the same protein, with no genome of any kind. Because there is no nucleic acid, treatments and sterilisation methods aimed at genomes have no effect.

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