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Discussion

Hepatitis B virus is unusual among DNA viruses because it

  • A.uses reverse transcription during replication
  • B.has a genome divided into several segments
  • C.replicates only in the cytoplasm
  • D.carries no protein coat

Answer: A

The hepadnaviruses carry DNA but copy an RNA intermediate back into DNA with a reverse transcriptase, a strategy otherwise associated with retroviruses. That shared enzyme is why some drugs are active against both hepatitis B virus and the human immunodeficiency virus.

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