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Tissue tropism of a virus refers to

  • A.its resistance to disinfectants
  • B.the shape of its capsid
  • C.the range of tissues it can productively infect
  • D.the speed at which it multiplies in a susceptible cell

Answer: C

Correct answer: the range of tissues it can productively infect

Tropism is determined first by which cells carry the receptor the virus binds and then by whether those cells can support the rest of the replication cycle. It is what makes rabies neurotropic, hepatitis viruses hepatotropic and rhinoviruses confined to the upper airway, and it explains the pattern of disease each produces far better than any property of the particle itself.

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