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An icosahedral capsid has rotational symmetry described as

  • A.6:4:2, with sixfold, fourfold and twofold axes
  • B.no rotational symmetry at all
  • C.5:3:2, with fivefold, threefold and twofold axes
  • D.2:2:2, with three twofold axes only

Answer: C

The icosahedron has axes of fivefold, threefold and twofold rotation, written 532, which is what allows a closed shell to be built from many copies of one protein. That economy matters because a small genome cannot encode a large, unique container.

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