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A prion is best described as

  • A.a defective virus needing a helper
  • B.a proteinaceous agent with no nucleic acid
  • C.a virus with an unusually small RNA genome
  • D.a naked circular RNA molecule

Answer: B

The term means a proteinaceous infectious agent, and the defining claim is that no nucleic acid can be demonstrated in it. That sets it apart from viroids, which are RNA without protein, and from viruses, which always carry a genome.

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