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Which pair correctly contrasts a viroid with a prion?

  • A.Both contain RNA, but only the prion has a capsid
  • B.Both contain protein and DNA in different proportions
  • C.A viroid is RNA without protein; a prion is protein without nucleic acid
  • D.A viroid is protein without nucleic acid; a prion is RNA without protein

Answer: C

The two are near mirror images. A viroid is a naked circular RNA with no coat, while a prion is proteinaceous with no demonstrable nucleic acid, so they represent fundamentally different infectious mechanisms and neither is a virus.

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