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An inactivated viral vaccine generally

  • A.confers lifelong immunity after a single dose
  • B.can cause the disease it protects against
  • C.needs only a very small quantity of antigen
  • D.requires additional doses after the first series

Answer: D

A killed preparation cannot replicate in the recipient, so the immune system meets only the antigen supplied. That makes the vaccine safe from causing infection but means high antigen concentrations and repeat doses are usually needed.

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