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Which sequence gives the correct order of the multiplication cycle?

  • A.Attachment, penetration, uncoating, synthesis, maturation, egress
  • B.Penetration, attachment, uncoating, synthesis, maturation, egress
  • C.Attachment, uncoating, penetration, maturation, synthesis, egress
  • D.Uncoating, attachment, penetration, synthesis, egress, maturation

Answer: A

Correct answer: Attachment, penetration, uncoating, synthesis, maturation, egress

The order is fixed by what each step requires of the one before. The particle must attach to its receptor before it can enter, must enter before the genome can be released, must release the genome before anything can be synthesised, and must synthesise the components before they can be assembled and released. Between uncoating and maturation lies the eclipse phase, when no infectious virus can be recovered from the cell at all.

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