Discussion
Which one of the following animal viruses contains double stranded RNA as genetic material?
Answer: D
The virus with a double stranded RNA genome is Reovirus.
Reoviruses (family Reoviridae, which also includes rotavirus, the main cause of severe infant diarrhoea) carry a segmented genome of 10-12 pieces of double stranded RNA, packed inside a double-layered protein capsid together with their own RNA polymerase.
The other three have single stranded RNA. Influenza virus has a segmented negative-sense single stranded genome. Rous sarcoma virus is a retrovirus with two copies of positive-sense single stranded RNA, copied into DNA by reverse transcriptase. Poliovirus is a picornavirus with one positive-sense single stranded RNA.
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