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The ..................... of the influenza-enveloped virus appear to be involved in attachment to the host cell receptor site.

  • A.Pili
  • B.Fimbriae
  • C.Haemagglutinin
  • D.Neuraminidase

Answer: C

Attachment is due to the haemagglutinin.

Haemagglutinin (HA) is a glycoprotein spike on the envelope of the influenza virus. It binds to sialic acid on the host cell surface, starting infection, and later mediates fusion of the viral envelope with the endosome membrane. It is named for its ability to agglutinate red blood cells and is the 'H' in names such as H1N1.

Neuraminidase, the other spike, acts at the end of infection by cutting sialic acid so that new virions can be released. Pili and fimbriae are attachment structures of bacteria, not of viruses.

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