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Deficiency of which mineral cause impaired immune function and Keshan disease?

  • A.Selenium
  • B.Chromium
  • C.Fluoride
  • D.Zinc

Answer: A

The mineral is Selenium.

Keshan disease is a cardiomyopathy first described in the Keshan region of China, where soils are poor in selenium. Selenium is part of the enzyme glutathione peroxidase, which protects cells from oxidative damage, and deficiency also impairs immune function. Selenium supplementation prevented the disease.

Chromium deficiency impairs glucose tolerance, fluoride deficiency raises the risk of dental caries, and zinc deficiency causes growth retardation, poor wound healing and impaired immunity, but none of them causes Keshan disease.

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