MH SET 2011: 7 August, Paper II, Life Sciences
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Life Sciences
Paper II
Time Allowed : 75 Minutes] [Maximum Marks : 100
Note : This Paper contains Fifty (50) multiple choice questions, each question
carrying Two (2) marks. Attempt All questions.
1. Dosage compensation in Drosophila 2. During homologous recombination
mediated by RecBCD enzyme in
and mammals differs by :
E.coli at chi site :
(A) Hyperactivation of single X
(A) Rec BCD proteins bind to DNA
in Drosophila males and to initiate recombination
inactivation of X in female
(B) Enzyme produces double
mammals stranded breaks in DNA
(B) Equalisation of transcription in (C) Helicase activity of enzyme
female Drosophila and starts unwinding DNA
hyperactivation of transcription (D) Branch migration is terminated
in female mammals 3. What is a Pseudogene ?
(C) Inactivation of X in Drosophila (A) A gene that is only expressed
at certain developmental stage
females and hyperactivation of
X in mammalian female (B) A non-functional gene
(C) A gene that contains a
(D) Equalisation of autosomal
mutation but is still functional
transcription in Drosophila and
(D) A sequence of DNA that is
reduced expression of one X in
slowly evolving to become an
mammals active gene
1 [P.T.O.
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4. How are proteins able to bind to 7. Virulence of Corynebacterium
DNA at specific sequences ? diphtheriae is due to :
(A) By interacting with sugar- (A) Phage conversion
phosphate backbone (B) Transformation
(B) By opening up double helix and (C) Transduction
forming bonds with the bases (D) Mutation
(C) By interacting with bases 8. The yeast two hybrid system is
through histone proteins designed to identify :
(D) By interacting with bases in the (A) All components of multiprotein
major and minor grooves of complex
double helix (B) Proteins required for binding
RNA polymerase
5. Black rats of identical genotypes on
mating produced offsprings (C) Two proteins that directly
consisting of 45 black, 15 cream interact with one another
coloured and 15 albino. Which of the (D) Two proteins involved in
following gene interactions may consecutive step of a metabolic
account for these results ? pathway
(A) Dominant epistasis 9. Diuron inhibits photosynthesis by
binding to :
(B) Recessive epistasis
(A) PS II
(C) Incomplete dominance and
(B) PS I
penetrance
(C) ATPase
(D) Complementary gene
(D) Cyt b6f
interactions
10. Which of the following properties of
6. People suffering from Cockayne water makes it a universal solvent ?
syndrome have defective :
(A) Hydrophobic bonds formed
(A) Double strand break repair between water and fatty acids
system (B) Strong covalent bonds formed
(B) Transcription coupled repair between water and salts
system (C) High dielectric constant of water
(C) Nucleotide excision repair (D) Hydrogen bonds formed between
system water and biochemical
(D) Mismatch repair system molecules
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11. Animal system is not able to synthe- 14. Which of the following statements
size ethanol in their body because regarding lipids is false ?
they lack one of the following
(A) Lipids can serve as energy
enzymes :
source for cells
(A) Alcohol dehydrogenase
(B) All cell membranes contain
(B) Pyruvate decarboxylase
lipids
(C) Pyruvate carboxylase
(D) Oxidase (C) All lipids can form bilayer
12. Which of the following is true for membranes
uncompetitive inhibitor of enzyme ? (D) Lipids can function as
(A) It decreases the affinity of the hormones
substrate for enzyme
15. Feedback inhibition differs from
(B) It increases the affinity of the
repression because feedback
substrate for enzyme
inhibition :
(C) It does not affect the affinity of
substrate for enzyme (A) is less precise
(D) It changes velocity but not (B) stops synthesis of new enzymes
V max of enzyme catalyzed (C) stops the action of pre-existing
reaction
enzymes
13. Which of the following statements
(D) is slow acting
is false for α-helix of proteins ?
(A) Number of amino acids per 16. Which of the following is the first
helical turn is 3.6 product of the CAM pathway ?
(B) Size of the helix is 5.4 Å (A) Oxaloacetate
(C) Right handed helices are (B) 3-phosphoglycerate
commonly found in proteins
(C) Malate
(D) Left handed helices are
commonly found in proteins (D) Pyruvate
3 [P.T.O.
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17. Fraction of the population dying in 21. Which of the following events could
each generation because of lead to the evolution of new gene
deleterious mutation at a locus is that contains exons from two or more
known as :
other genes ?
(A) Risk population
(A) Domain duplication
(B) Mutational load
(B) Domain shuffling
(C) Genetic load
(C) Gene conversion
(D) Lethal linkage group
18. Characteristics that have arisen as (D) Gene duplication
a result of common evolutionary 22. Mitochondrial DNA can be used to
descent are said to be : trace parental lineage because it is :
(A) Analogous (A) Paternally transmitted,
(B) Persimonious recombines at low rate
(C) Morphotypes (B) Maternally transmitted does
(D) Homologous not recombine
19. Categories of species vulnerable to (C) Maternally transmitted,
extinction include all of the following
recombines at low rate
except those that :
(D) Biparental transmission, does
(A) have high genetic variability
not recombine
(B) are hunted by poachers or
harvested by people 23. A given population with 0.03%
(C) have declining population size frequency of phenylketonuria can be
said to be :
(D) are local endemic species
20. A classical example of ortho- (A) in Hardy-Weinberg equilibrium
evolutionary process is evolution of : (B) under selection and migration
(A) Man (C) maintaining balance between
(B) Horse mutation and selection
(C) Fish (D) not in Hardy-Weinberg
(D) Amphibia equilibrium
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24. If genetic code is tetraplet, then what 27. Which of the following is the correct
is the possible number of codons sequence for T-cell differentiation in
which would code for 20 amino thymus ?
acids ? (A) Double negative, Single
(A) 32 positive, Double positive
(B) 64 (B) Double positive, Double
(C) 256 negative, Single positive
(D) 512 (C) Double negative, Double
positive, Single positive
25. Lysosomes have a very low pH. This
is achieved by : (D) Double positive, Single
negative, Double negative
(A) Proton pumps that transfer
protons down the concentration 28. If mouse IgG1 is injected as an
gradient antigen in mice, it would generate :
(B) Release of energy by proton (A) Anti-isotypic antibodies
pumps (B) Anti-allotypic antibodies
(C) Proton pumps against the (C) Anti-idiotypic antibodies
concentration gradient
(D) No antibodies
(D) Synthesizing acidic components
29. The human immunodeficiency virus
26. The first step of “proof-reading” interacts with one of the following
during protein synthesis is carried to gain entry into the cells of the
out by : immune system :
(A) Ribosomes (A) CD-4
(B) Initiation factors (B) CD-19
(C) Elongation factors (C) CD-8
(D) Aminoacyl t-RNA synthetase (D) CD-25
5 [P.T.O.
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30. Nuclear matrix is : 33. The primary causative agents of
(A) A complex of histone proteins acid rain are :
and DNA that provides (A) Sulphur dioxides and lead
structural network throughout dioxides
the nucleus (B) Sulphur dioxides and nitrogen
(B) A mixture of DNA, RNA and dioxides
proteins that make up nucleus (C) Nitrogen dioxides and lead
dioxides
(C) Network of microtubules that
provide structural foundation to (D) Sulphur dioxides and carbon
nucleus dioxides
(D) A complex network of protein 34. Natural products from one of the
following is used as nutraceuticals,
and RNA fibrils that make up
pharmaceutical and cosmaceutical :
nuclear substructure
(A) Aloe vera
31. Which of the following is TRUE for
(B) Curcuma longa
secondary messenger molecules ?
(C) Stevia rebaudiana
(A) They are hormones that initiate
signaling pathway (D) Morinda citrifolia
(B) They are receptors that bind to 35. Protection of its occupancy area
encapsulates other species defines
hormones and activate a
the :
pathway
(A) Flagship species
(C) They are internal moleules that
(B) Umbrella species
transduce a signal inside the
cell (C) Key-stone species
(D) They are transcriptional (D) Exotic species
activators that function at the 36. An assemblage of populations of
end of a pathway plants, animals, bacteria and fungi
that live in an area and interact with
32. Carmine dye is obtained from :
each other defines :
(A) Cochined insects
(A) Biological community
(B) Lac insects
(B) Ecosystem
(C) Aphids (C) Population
(D) Bumble bees (D) Biome
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37. In India, air quality is monitored 41. A species is designated as
using levels of : “vulnerable” when :
(A) SPM, RPM, CO2 and NO2
(A) It is not critically endangered
(B) SPM, RPM, SO2 and NO2
but is facing a high risk of
(C) RPM, CO2, SO2 and NO2
extinction in the wild in the
(D) SPM, CO2, SO2 and NO2
near future
38. DNA fingerprinting makes use of the
following : (B) It is not critically endangered
(A) Retroposon rearrangements in but is facing a high risk of
an organism extinction in the wild in the
(B) Differences in gene families immediate future
(C) Polymorphism in splicing (C) It is critically endangered
pattern already
(D) Sequence heterogeneity and
(D) 50% population got extinct in
polymorphism
the last 10 years
39. Which one of the following would
need conservation on higher 42. Metagenomics refers to :
priority ?
(A) Genomics of metabolic pathways
(A) Species which flowers rarely
(B) Genomics of metallothionine
and has specific pollinator
(B) Species which flowers normally gene
and is wind pollinated (C) Genomic sequencing of pool of
(C) Species which flowers rarely DNA fragments
and has non-specific pollinator
(D) Genomes of bacteria associated
(D) Species which reproduces
with metal bioremediation
vegetatively
40. Species represented by a group of 43. Alpha, beta and gamma diversity
populations throughout distribution refer to :
range is called : (A) Genetic diversity
(A) Taxonomic species
(B) Landscape diversity
(B) Biological species
(C) Synthetic species (C) Species diversity
(D) Polyphyletic species (D) Population diversity
7 [P.T.O.
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44. Which of the following processes 47. Osmotolerant yeasts are able to grow
at high salt concentrations because
does not generate ATP/GTP ?
their cytoplasm contains high
(A) Oxidative phosphorylation concentration of :
(A) Divalent cations
(B) TCA cycle
(B) Lipids
(C) Glycolysis
(C) Amino acids
(D) Calvin’s cycle (D) Polyalcohols
45. By which of the following 48. In a seed, which of the following
represents sporophytic tissue ?
mechanisms does an enzyme
(A) Testa
increase the rate of a reaction ?
(B) Cotyledon
(A) It provides energy to start the (C) Endosperm
reaction (D) Hypocotyle
(B) It increases the rate of collision 49. The type of nitrogenous excretory
product, in animals, primarily
between molecules
depends on :
(C) It lowers the activation energy (A) The quantum of protein
of the reaction availability to the animals
(B) The quantum of food
(D) It changes the equilibrium
availability to the animals
point of the reaction
(C) Starvation
46. The most selective antimicrobial (D) The quantum of water
activity would be exhibited by a availability to the animals
drug that : 50. Development of gametophyte from
sporophyte without formation of
(A) Inhibits cell wall synthesis spores is called :
(B) Inhibits protein synthesis (A) Homospory
(B) Apospory
(C) Injures plasma membrane
(C) Oospory
(D) Inhibits nucleic acid synthesis (D) Haplospory
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ROUGH WORK
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ROUGH WORK
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Source: Savitribai Phule Pune University. Question paper published by Savitribai Phule Pune University.