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MH SET 2023: 26 March, Paper II, Life Sciences

  • Date: 26 March 2023
  • Paper code: MAR-34223
  • Series: A
  • Language: Bilingual
  • 20 pages
MH SET 2023 question paper, 26 March 2023, Paper II, Life Sciences, page 1 of 20
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Test Booklet Code & Serial No.
                                                                                                                      A
                                                             LIFE SCIENCE
Signature and Name of Invigilator                                                         Seat No.
1. (Signature) .........................................                                                    (In figures as in Admit Card)
      (Name) ................................................                     Seat No. ..............................................................
2. (Signature) .........................................                                               (In words)

      (Name) ................................................                 OMR Sheet No.
MAR - 34223                                                                                                 (To be filled by the Candidate)
Time Allowed : 2 Hours]                                                                                 [Maximum Marks : 200
Number of Pages in this Booklet : 20                                                     Number of Questions in this Booklet : 100
                      Instructions for the Candidates
1.         Write your Seat No. and OMR Sheet No. in the space provided              1.
           on the top of this page.
2.         This paper consists of 100 objective type questions. Each question
           will carry two marks. All questions of Paper II will be compulsory.      2.
3.         At the commencement of examination, the question booklet
           will be given to the student. In the first 5 minutes, you are            3.
           requested to open the booklet and compulsorily examine it as
           follows :
           (i)      To have access to the Question Booklet, tear off the
                    paper seal on the edge of this cover page. Do not accept                (i)
                    a booklet without sticker-seal or open booklet.
           (ii)     Tally the number of pages and number of questions in
                    the booklet with the information printed on the cover                   (ii)
                    page. Faulty booklets due to missing pages/questions
                    or questions repeated or not in serial order or any
                    other discrepancy should not be accepted and correct
                    booklet should be obtained from the invigilator within
                    the period of 5 minutes. Afterwards, neither the Question
                    Booklet will be replaced nor any extra time will be
                    given. The same may please be noted.
           (iii)    After this verification is over, the OMR Sheet Number
                                                                                            (iii)
                    should be entered on this Test Booklet.
4.         Each question has four alternative responses marked (A), (B),
           (C) and (D). You have to darken the circle as indicated below on         4.                      (A), (B), (C)   (D)
           the correct response against each item.
           Example : where (C) is the correct response.

                              A        B                 D                                            (C)
5.         Your responses to the items are to be indicated in the OMR                                       A         B             D
           Sheet given inside the Booklet only. If you mark at any place
           other than in the circle in the OMR Sheet, it will not be evaluated.     5.
6.         Read instructions given inside carefully.
7.         Rough Work is to be done at the end of this booklet.                     6.
8.         If you write your Name, Seat Number, Phone Number or put                 7.
           any mark on any part of the OMR Sheet, except for the space
                                                                                    8.
           allotted for the relevant entries, which may disclose your
           identity, or use abusive language or employ any other unfair
           means, you will render yourself liable to disqualification.
9.         You have to return original OMR Sheet to the invigilator at the
           end of the examination compulsorily and must not carry it with           9.
           you outside the Examination Hall. You are, however, allowed
           to carry the Test Booklet and duplicate copy of OMR Sheet on
           conclusion of examination.
                                                                                    10.
10.        Use only Blue/Black Ball point pen.
                                                                                    11.
11.        Use of any calculator or log table, etc., is prohibited.
12.        There is no negative marking for incorrect answers.                      12.
MH SET 2023 question paper, 26 March 2023, Paper II, Life Sciences, page 2 of 20
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MH SET 2023 question paper, 26 March 2023, Paper II, Life Sciences, page 3 of 20
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MAR - 34223/II—A
                                   Life Science
                                       Paper II
Time Allowed : 120 Minutes]                                     [Maximum Marks : 200
Note : This Paper contains Hundred (100) multiple choice questions. Each question
         carrying Two (2) marks. Attempt All questions.

1.   Phages are collected from an infected         2.   Mark the most INCORRECT
                                                        statement with respect to
     E.coli donor strain of genotype ser+,              mammalian below :
     gly+, leu+ and used to transduce a                 (A) Very small quantity of oxygen
                                                             is transported as dissolved in
     recipient of genotype ser - , gly - ,
                                                             plasma
     leu – .   The   treated     recipient              (B) Least amount of carbon dioxide
     population is plated on a minimal                       is transported as dissolved in
                                                             plasma
     medium supplemented with leucine                   (C) Increased carbon dioxide in
     and serine. Many colonies grew.                         blood favours release of oxygen
                                                             from hemoglobin
     Which     one   of    the   following
                                                        (D) Maximum carbon dioxide is
     combination      of     genotypes    is                 transported as bound to
     appropriate for the colonies that                       hemoglobin
                                                   3.   The following are certain statements
     grew ?                                             regarding secondary metabolites
                                                        found in plants. Among the
     (A) ser–, gly–, leu+; ser+, gly–, leu+;
                                                        following, which is FALSE ?
          ser+, gly–, leu–                              (A) Alkaloids      are      nitrogen
                                                             containing compounds
     (B) ser+, gly+, leu+; ser+, gly–, leu+;            (B) All terpenes are derived from
          ser+, gly–, leu–                                   five carbon isoprene units
                                                        (C) Flavanoids contain 15 carbons
     (C) ser–, gly+, leu+; ser+, gly+, leu+;                 arranged in two aromatic rings
                                                             connected by a 3 carbon bridge
          ser+, gly+, leu–
                                                        (D) Phenylalanine          is     an
     (D) ser–, gly+, leu+; ser+, gly–, leu+;                 intermediate        in      the
                                                             biosynthesis of most plant
          ser+, gly–, leu–                                   alkaloids

                                               3                                    [P.T.O.
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4.   In the absence of oxygen, the                 6.   During which of the following stages

     metabolic fate of pyruvic acid will                of meiosis, does the synaptonemal

     be :                                               complex breakdown leading to the
                                                        separation     of    two   homologous
     (A) Its partial oxidation will take
                                                        chromosomes ?
            place
                                                        (A) Zygotene
     (B) Its complete oxidation will take
                                                        (B) Pachytene
            place
                                                        (C) Diplotene
     (C) It will be utilized for reoxidation
                                                        (D) Diakinesis
            of NADH
                                                   7.   Which of the following statements
     (D) It will be utilized depending on               about embryo sac development in

            energy need                                 plants is NOT CORRECT ?

                                                        (A) Embryo sac is mostly a 7-celled
5.   Which of the following statement for
                                                            structure
     Gibberellins is NOT CORRECT ?
                                                        (B) Plumbago type of embryo sac is
     (A) Gibberellins regulate transition
                                                            derived from four megaspore
            from juvenile to adult phases                   nuclei

     (B) Gibberellins      promote     seed             (C) Synergids are elongated cells

            germination                                     present at the micropylar end of
                                                            the embryo sac
     (C) Gibberellins can regulate cell
                                                        (D) Polygonum type of embryo sac
            cycle
                                                            is derived from the micropylar
     (D) Gibberellins are synthesized via                   megaspore of the tetrad and is
            the terpenoid pathway                           eight nucleate

                                               4
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8.   In chick, gastrulation involves             11. Match the antibiotics in Column A
     inward movement of cells through                 with their appropriate antimicrobial
     the :                                            activity from Column B :

     (A) Blastoderm                                                 Column A

     (B) Yolk                                         I.    Gatifloxacin

     (C) Cleavage furrow                              II. Acyclovir

                                                      III. Mefloquine
     (D) Primitive streak
                                                      IV. Griseofulvin
9.   Heart muscles normally cannot be
     tetanized because :                                            Column B

     (A) It receives O2 directly from the             (a) Antifungal agent

         blood it pumps                               (b) Antibacterial agent

     (B) Its absolute refractory period is            (c)   Antiviral agent

         long                                         (d) Antiprotozoal agent

     (C) It does not contain more Ca2+                        I       II       III      IV

     (D) It does not possess Ca 2+                    (A)     (b)     (a)      (d)      (c)

         channels                                     (B)     (b)     (c)      (d)      (a)

10. In       which   of   the   following             (C)     (d)     (c)      (a)      (b)
     evolutionary processes random                    (D)     (b)     (d)      (c)      (a)
     changes in allele frequency can lead        12. In the prokaryotic protein synthesis,
     to loss of genetic diversity ?                  initiation site of mRNA consists
                                                     of..............codon preceeded by ..........
     (A) Recombinant event                           (A) AUG, Shine-Dalgamo poly-
                                                           purine hexamer
     (B) Gene flow
                                                     (B) GUG, 5'-Cap
     (C) Genetic drift                               (C) UAG', m7G
                                                     (D) AGG', Methylated guanosine
     (D) Spontaneous selection

                                             5                                           [P.T.O.
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13. Which of the following sigma             16. Which of the following statements about
    subunit     of   prokaryotic   RNA           phytochrome is NOT CORRECT ?
                                                 (A) Phytochrome contains PAS,
    Polymerase is responsible for
                                                     GAF, PHY and PRD domains
    transcription of housekeeping                (B) Phytochrome is a light
                                                     regulated protein kinase
    genes ?
                                                 (C) Phytochrome are encoded by a
    (A) Sigma 32                                     multigene family
                                                 (D) Phytochrome are normally
    (B) Sigma 54
                                                     found in the chloroplast
    (C) Sigma 70                             17. In which of the following the
                                                 hydrogen bond is NOT formed ?
    (D) Sigma 28
                                                 (A) between water and amino group
14. Arabidopsis AtNHX1 gene encodes                  of an amino acid
                                                 (B) between carbonyl group of
    a tonoplast Na+/H+ antiporter used               protein and amino group of
    to develop transgenic plants to                  protein
                                                 (C) between hydroxy group of
    improve :                                        alcohol and water
    (A) drought tolerance                        (D) between methyl group of
                                                     alanine and water
    (B) salinity tolerance                   18. Heritability     estimates      the
                                                 proportion of :
    (C) pest resistance
                                                 (A) genetic variation in a group
    (D) pathogen resistance                          that can be attributed to
                                                     phenotype
15. Which one is NOT an agglutination
                                                 (B) Phenotypic variation in an
    test ?                                           individual that can be
                                                     attributed to genes
    (A) Widal test
                                                 (C) Phenotypic variation in a group
    (B) Coombs test                                  that can be attributed to genes
                                                 (D) Environmental variation in a
    (C) Mantoux test                                 group that can be attributed to
    (D) Blood group test                              phenotype

                                         6
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19. Classically, prions are recognized as       21. Name the mechanism by which new
                                                    alleles appears in a population.
    agent causing :
                                                    (A) Karyokinesis
    (A) Schizophrenia
                                                    (B) Mutation
    (B) Cerebral stroke                             (C) Heredity
    (C) Alzheimer's disease                         (D) Cytokinesis

    (D) Madcow disease                          22. I : Acetylation and deacetylation of
                                                        chromatin is associated with
20. Which of the following statements
                                                        masking and unmasking of
    about crossing over is true ?                       chromatin for transcription.

    (A) There is a greater probability              II : The activity of HAT and HDAC
                                                         is associated with condensing
         for a crossover to occur between
                                                         and relaxing the chromatin.
         2 genes farther apart from the
                                                    Select the correct answer :
         genes nearer to each other                 (A) I only is correct
    (B) There is a lesser probability for           (B) II only is correct
         a crossover to occur between 2             (C) I is correct and II is wrong
         genes farther apart from the               (D) II is correct and I is wrong

         genes nearer to each other             23. Patch clamp technique is used in
                                                    biological membrane studies. What
    (C) Probability of crossover between
                                                    is it mainly used to detect ? Select
         2    genes     is    inversely             the correct option.
         proportional to the distance               (A) To estimate ion flow through
                                                        ion channels
         between them
                                                    (B) To quantify membrane proteins
    (D) Maximum         frequency      of
                                                    (C) To estimate membrane lipids in
         recombination that can result                  outer leaflet
         from crossing over between                 (D) To prove lateral diffusion of
         linked genes is 100%                            lipids in the membrane

                                            7                                     [P.T.O.
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24. During in vitro DNA synthesis               27. Anatomically the conversion of
    which       of      the   following             series heart to parallel heart with
    radionucleotide is most preferred ?             separation of oxygenated and

    (A) 3H labelled dTTP                            deoxygenated blood circulation

    (B) 14C labelled dUTP                           observed as primary feature in the

                                                    following evolutionary sequence in
    (C)    -32P labelled dTTP
                                                    chordate evolution :
    (D)   -32P labelled dTTP
                                                    (A) Agnatha to Fishes
25. The nucleotides from the 5'end of the
                                                    (B) Fishes to Amphibia
    bacterial tRNA precursor are
                                                    (C) Amphibia to Reptiles
    cleaved during the maturation
                                                    (D) Birds to Mammals
    process. Which enzyme is involved
                                                28. Downy     mildew     is    the   most
    in this process ?
                                                    destructive fungal disease of
    (A) RNase P
                                                    grapevines and is caused by :
    (B) RNase Z
                                                    (A) Plasmopara viticola
    (C) t-RNA nucleotidyl transferase               (B) Ascochyta rabiei
    (D) S1 nuclease                                 (C) Puccinia striiformis

26. Which one of the following is not a             (D) Sclerospora graminicola

    DNA depurinating agent ?                    29. Presence of parasite on the surface
                                                    of the body of host is called as :
    (A) Ethyl ethane sulphonate
                                                    (A) Infestation
    (B) Nitroso guanidine
                                                    (B) Infection
    (C) Dimethyl nitrosamine
                                                    (C) Pollution
    (D) Methyl ethane sulphonate
                                                    (D) Contamination
                                            8
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30. In which one of the following              33. The t-RNA is specific for an amino
    phenomena, coding region of the                acid and it differs in sequence of
    gene is affected, hence new protein            nucleotides. All t-RNA molecules
    is formed ?                                    contain a base paired stem that

    (A) Heterotopy                                 terminates in the CCA sequence
                                                   at :
    (B) Heterotypy
                                                   (A) 3' termini
    (C) Heterochrony
                                                   (B) 5' termini
    (D) Heterometry
                                                   (C) anticodon arm
31. Out of the following Helminthes
    which one of the groups is solitary            (D) spacer arm

    and free living representatives ?          34. In Larval amphibians, which of the

    (A) Turbellaria                                following neuropeptides controls the
                                                   release of thyroid stimulating
    (B) Trematoda
                                                   hormone (TSH) that in turn
    (C) Cestoda
                                                   regulates      metamorphosis      by
    (D) Nematoda                                   stimulating the secretion of T3 & T4.
32. The gill like structure that is non-           (A) Thyrotropin releasing hormones
    respiratory in function in the                        (TRH)
    branchial chamber of some of the
                                                   (B) Gonadotropin          releasing
    teleosts is known as :
                                                          hormone (GnRH)
    (A) Suprabranch
                                                   (C) Corticotropin releasing hormone
    (B) Holobranch                                        (CRH)
    (C) Hemibranch                                 (D) Growth hormone releasing
    (D) Pseudobranch                                      hormone (GHRH)
                                           9                                    [P.T.O.
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35. DNA is NOT present in which one             39. What is the pI value of a non-
    of the following ?                              standard amino acid X, whose pK1,

    (A) Bacteriophage T4                            pK2 and pK3 values are 2.5, 7.5 and

    (B) Tobacco Mosaic Virus (TMV)                  9.0 ?

    (C) Adenovirus                                  (A) 8.25       (B)    5.0
    (D) Chloroplast                                 (C) 5.75       (D)    6.33
36. Proof reading activity of DNA
                                                40. The diploid maize (2n = 2X = 20)
    Polymerase is :
                                                    treated with colchicine to induce
    (A) 3'      5' exonuclease activity
                                                    tetraploidy. However, it showed
    (B) 5'      3' exonuclease activity
                                                    sterility because :
    (C) Endonuclease activity
                                                    (A) Problems in mitosis
    (D) 5'      3' polymerase activity
37. The deamination of adenine leads to             (B) Induced male sterility
    formation of :                                  (C) Problems in meiosis
    (A) Cytosine
                                                    (D) Induced self-incompatibility
    (B) Hypoxanthine
                                                41. How do viruses gain entry to a host
    (C) Xanthine
                                                    cell ?
    (D) Uracil
                                                    (A) By dissolving a piece of the host
38. In enzyme kinetics the rate constant
                                                        cell membrane
    Kcat refers to :
    (A) Michaelis-Menten Constant                   (B) By binding to an antibody site

    (B) Substrate concentration at                      on the host cells

         Vmax                                       (C) By diffusion through the cell
    (C) Turn over number                                membrane
    (D) Total number of active sites on             (D) By binding to a receptor site on
         the enzyme                                     the host cell
                                           10
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42. The primary mode of transmission             46. In an ecosystem.........requires
    for spread of polio virus is :                   maximum energy.
    (A) Ingestion (Oral-fecal)                       (A) Primary producer

    (B) Respiratory droplets                         (B) Primary consumer

    (C) Sexual transmission                          (C) Secondary consumer
                                                     (D) Decomposer
    (D) Blood transfusion
                                                 47. Which one of the following 'biomes'
43. The process of using bacteria for
                                                     does not have fauna & flora
    extraction of valuable metals in                 characteristic of tropical rain
    mining industry is known as :                    forests ?
    (A) Biodegradation                               (A) South America
    (B) Bioleaching                                  (B) South Central Africa
    (C) Biosorption                                  (C) Central Africa

    (D) Bioremediation                               (D) Australia
                                                 48. In a pond ecosystem, the bottom
44. The only poisonous lizard found in
                                                     area where production is less than
    South America is :
                                                     respiration is called as :
    (A) Calotes
                                                     (A) Limnetic zone
    (B) Hemidactylus                                 (B) Benthic zone
    (C) Heloderma                                    (C) Profundal zone
    (D) Mabuya                                       (D) Intertidal zone
45. Which of the following is not a              49. "Each creature on earth was

    developmental stage in the life cycle            separately created" is :
                                                     (A) a belief and does not fall within
    of Fasciola hepatica ?
                                                         the scope of experimental
    (A) Cercaria
                                                         science
    (B) Cystecircus                                  (B) best described as a natural law
    (C) Metacercaria                                 (C) a testable hypothesis
    (D) Sporocysts                                   (D) a theory
                                            11                                    [P.T.O.
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50. RUBISCO is encoded by :                      53. Which of the following fossil organs
    (A) Mitochondrial DNA                            DOES NOT belong to pentoxylon
    (B) Plastid DNA and mitochondrial                plant ?
         DNA                                         (A) Nipaniophyllum
    (C) Mitochondrial       DNA      and             (B) Sahnia
         Chloroplast DNA                             (C) Carnoconites
    (D) Nuclear DNA and Chloroplast                  (D) Williamsonia
         DNA                                     54. Which type of interaction that
51. The following are the characteristics            involves an individual sacrificing
    of k-selected animals except :                   some of its own reproductive success
    (A) Energy spent per offspring is                for the benefit of the other ?
         high                                        (A) Co-operation
    (B) A few offsprings are produced                (B) Mutualism
         that mature late and live longer
                                                     (C) Commensalism
    (C) Type-II survivorship pattern is
                                                     (D) Altruism
         observed
                                                 55. Many species of bony fishes swim
    (D) Semelparous
                                                     together in a coordinated fashion,
52. Darwin's finches, which have
                                                     called schooling.
    adapted to different Galapaqos
                                                     Which one of the following is not
    islands have different bill sizes,
                                                     true   for    the   advantages    of
    shapes colouration and body size.
                                                     schooling ?
    This is an example of :
                                                     (A) Avoiding predators
    (A) Homology
                                                     (B) Locating food sources
    (B) Convergence
                                                     (C) Increases reproductive success
    (C) Parallelism
                                                     (D) Attainment of faster growth
    (D) Adaptive radiation
                                            12
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56. For developing transgenic mustard          58. Match the following products with

                                                   their method of production :
    variety DMH-11 Bar, Barnase and
                                                                Column A
    Barstar genes were obtained from :
                                                   I.    Beer

    (A) Bacillus amyloliquefaciens                 II. Wine

                                                   III. Vinegar
    (B) Bacillus thuringiensis
                                                   IV. Spirit
    (C) Agrobacterium tumefaciens
                                                                Column B

    (D) Erwinia uredovora                          (a) Fermentation of grape juice
                                                         with yeast
57. Nowadays blood glucose is measured
                                                   (b) Fermentation of malted grain
    by glucometer, where the glucose is                  and yeast

    measured by :                                  (c)   Fermentation followed by
                                                         distillation of ethanol
    (A) rate   of   disappearance    of
                                                   (d) Fermentation         to     produce
        substrate                                        ethanol followed by Acetobacter
                                                         metabolism of ethanol
    (B) rate of appearance of product
                                                   Codes :
    (C) rate of electron flow from
                                                         I      II    III    IV

        glucose to an electrode surface            (A)   (b)    (a)   (d)    (c)

                                                   (B)   (c)    (a)   (d)    (b)
    (D) rate of electron flow from
                                                   (C)   (c)    (b)   (a)    (d)
        electron donor to glucose
                                                   (D)   (a)    (d)   (b)    (c)
                                          13                                        [P.T.O.
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59. Which phytoremediation approach             62. For insertion of DNA into a suitable
    involves reduced mobility         of            vector several methods are used and
                                                    homopolymer tailing is one of them.
    contaminants through sorption onto
                                                    Which specific enzyme is used in
    plant root surfaces ?                           this method to synthesize
    (A) Phytostabilization                          homopolymer tail ?
                                                    (A) T4 DNA ligase
    (B) Rhizofiltration
                                                    (B) Polynucleotide kinase
    (C) Phytovolatilization
                                                    (C) Terminal deoxynucleotidyl
    (D) Rhizodegradation                                transferase
60. Blue white screening is done to :               (D) S1 nuclease
                                                63. Which region of CD spectrum gives
    (A) Check expression of cloned gene
                                                    details of secondary structure of a
    (B) Check the presence of a cloned              protein ?
         insert in a plasmid                        (A) Far–UV region
                                                    (B) Near–UV region
    (C) Check the presence of a plasmid
                                                    (C) Entire–UV region
         in bacteria
                                                    (D) Both UV and Visible region
    (D) Check the copy number of                64. In RIA; radiolabelling is done for :
         cloned insert in a plasmid                 (A) Antigen
61. A vector is designed to replicate in            (B) Antibody
    both, E.coli and Streptomyces. It is            (C) Antigen antibody complex
                                                    (D) Secondary antibody
    reconstructed from E.coli plasmid
                                                65. For which distribution mean and
    and streptomyces plasmid. What is
                                                    variance are equal ?
    the type of such vectors ?
                                                    (A) Binomial distribution
    (A) Phagemid vectors
                                                    (B) Chi-square distribution
    (B) Shuttle vectors
                                                    (C) Poisson distribution
    (C) BAC vectors
    (D) YAC vectors                                 (D) Normal distribution

                                           14
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66. One of the following zones of                70. Why Dinococcus radiodurans is able
    electromagnetic spectrum is used for             to survive massive exposure to
    passive optical remote sensing :
                                                     radiation ?
    (A) X-Ray
                                                     (A) It produces a thick shell which
    (B) Visible band
                                                         acts as a shield against
    (C) Microwave
                                                         radiation
    (D) Radiowave
                                                     (B) It has unique DNA repair
67. The heat shock response in E.coli
                                                         mechanism
    increases the level of a regulator
    molecule that binds to promoter for              (C) Its cell secrete slime
    RNA polymerase to increase the                   (D) It has many copies of genes
    production of heat shock protein :                   encoding for DNA repair
    (A) pppGppp                                  71. How bacterial cells transport
          H/ 32 factor                               oxygen and water across the cell
    (B)
                                                     membrane ?
    (C) AppppA
                                                     (A) Group translocation
    (D) Diadeosine-3'
68. Which of the following protein                   (B) Active transport
    inhibits kinase activity of yeast CDK            (C) Facilitated diffusion
    by phosphorylation during G2                     (D) Simple passive diffusion
    checkpoint ?                                 72. Which of the following component
    (A) Wee 1                                        from Halobacterium salinarum
    (B) CDC 25
                                                     absorb the energy in sunlight and
    (C) CDC 20
                                                     generates proton motive force (pmf)
    (D) RB (Retinoblastoma)
                                                     through phocycling under anaerobic
69. Genome size refers to the amount
    of DNA contained in a :                          or microaerobic conditions ?
    (A) Haploid genome                               (A) Chlorosomes
    (B) Diploid genome
                                                     (B) Bacteriochlorophylla
    (C) Haploid as well as diploid
        genome                                       (C) Bacteriorhodopsin
    (D) Complete organism                            (D) Photosystem-I
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73. One of the signalling molecules used           77. Diffusion, formation of stable
    for bacterial cell-cell communication              concentration          gradient   and
    are :                                              functioning of hedgehog proteins
    (A) N-acetyl hydroxy laccase                       critically depend on their association
    (B) N-acyl homoserine laccase
                                                       with :
    (C) N-acetyl homoserine lactone
                                                       (A) Fatty acids
    (D) N-acyl homoserine lactone
74. The embryonic origin of squamous                   (B) Cholesterol
    cell carcinoma is :                                (C) Lenolenic acid
    (A) Endoderm                                       (D) Carboxylic acid
    (B) Mesoderm
                                                   78. The visceral arches IV to VII of
    (C) Mesenchymal tissue
    (D) Ectoderm                                       basic vertebrate body plan gave rise
75. The kidney transplantation from one                to one of the following systems
    individual to another is a :                       during their evolution :
    (A) Isograft                                       (A) Digestive system
    (B) Allograft
                                                       (B) Respiratory system
    (C) Autograft
                                                       (C) Excretory system
    (D) Xenograft
76. When you are continuously exposed                  (D) Nervous system
    to specific antigen for a longer period        79. Widely          used       molecular
    which of the following statements
                                                       characterisation technique for
    falls wrong ?
                                                       identification of different strains of
    (A) There will be antibody class
         switching happening in the                    bacteria is :
         body                                          (A) Serological         identification
    (B) There       will     be   affinity                 analysis
         maturation happening in the
                                                       (B) 5S ribosomal RNA genes
         body
    (C) The body produces same                             analysis
         antibody always                               (C) 16S ribosomal RNA genes
    (D) There will be primary and                          analysis
         secondary response happening                  (D) Total mRNA genes analysis

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80. Translocation in philadelphia                  84. The vitamin which plays an
    chromosome :                                       important role in conversion of
     (A) 19 to 21 chromosome region                    proline to hydroxyproline in
                                                       building the appropriate collagen
         exchange
                                                       protein is :
     (B) 9 to 21 chromosome region
                                                       (A) Vitamin A
         exchange
                                                       (B) Vitamin B
     (C) leads to the production of black              (C) Vitamin C
         urine                                         (D) Vitamin D
     (D) leads      to     the    chronic          85. In Eukaryotes, the promoter
         myelogenous leukemia                          sequence TATA box is located at :
81. Paradox related to protein folding is :            (A) 10 to 15 base pairs upstream of
     (A) C. Value paradox                                  transcription site
                                                       (B) 10 to 15 base pairs downstream
     (B) Sherman paradox
                                                           of transcription site
     (C) Lombard's paradox
                                                       (C) 25 to 35 upstream of trans-
     (D) Levinthal's paradox                               cription site
82. Glucose    6    phosphate     and                  (D) 25 to 35 downstream of
    glyceraldehyde 3 phosphate are                         transcription site
    processed by glycolysis. How many              86. Which one is NOT true in case
     ATP molecules will be generated                   of CpG ?
     respectively from each ?                          (A) CpG are island promoters
                                                       (B) CpG are involved in gene
     (A) 2 ATP and 3 ATP
                                                           regulation at chromatin level
     (B) 3 ATP and 3 ATP
                                                       (C) CpG within promoters are
     (C) 3 ATP and 2 ATP                                   methylated
     (D) 4 ATP and 2 ATP                               (D) Methylation in CpG is
83. How many ATP molecules are                             associated with 'C'.
    formed when sucrose is metabolized             87. Ubiquitin ligases are associated
                                                       with degradation of :
    during glycolysis by substrate level
                                                       (A) Protein
    phosphorylation ?
                                                       (B) DNA
     (A) 2               (B) 4                         (C) RNA
     (C) 8               (D) 00                        (D) Carbohydrates
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88. Which one of the following is not             92. Given the abbreviations, which of
    readily absorbed in the small                     the following equations describe best
                                                      the glomerular filtration rate
    intestine ?
                                                      (GFR) ?
    (A) Na+         (B) Cl –                          Kf – glomerular              capillary
    (C) K+          (D) Mg++                                   filtration coefficient
                                                      P g – glomerular hydrostatic
89. The menstrual cycle of human
                                                               pressure
    female is the example of biorhythm                P b – hydrostatic pressure of
    known as :                                                 Bowmen's capsule
    (A) Ultradian rhythm                              Gc – Osmotic pressure of plasma
                                                               proteins in the glomerular
    (B) Tidal rhythm                                           capillary
    (C) Infradian rhythm                              Bc – Osmotic pressure of proteins
                                                               in Bowmen's capsule
    (D) Circadian rhythm
                                                      (A) GFR = Kf × (Pg–Pb–Gc + Bc)
90. Which of the following heat shock
                                                      (B) GFR = Kf + (Pg + Pb +Gc + Bc)
    proteins is present in almost every
                                                      (C) GFR = Kf – (Pg–Pb + Gc – Bc)
    compartment of the Eukaryotic cell ?              (D) GFR = Kf × (Pg + Pb– Gc – Bc)
    (A) Hsp60       (B) Hsp70                     93. Name the water soluble non-B
    (C) Hsp90       (D) Hsp100                        complex vitamin that is structurally
                                                      similar to a monosaccharide :
91. Muscle overactivity like long
                                                      (A) Pantothenic acid
    running needs more O 2 to the
                                                      (B) Biotin
    muscles. This is achieved by release              (C) Niacin
    of   more     O 2 from     the   blood            (D) Ascorbic acid
    hemoglobin due to :                           94. The amino acid involved as a
    (A) more blood flows to the muscles               precursor in auxin biosynthesis is :
    (B) accummulation of lactic acid and              (A) Serine       (B) Tryptophan
                                                      (C) Valine       (D) Tyrosine
         increasing pH
                                                  95. In aerobic respiration, oxidation of
    (C) accummulation of lactic acid and              1 molecule of glucose gives rise to
         reducing pH                                  how many ATPs ?
    (D) Increased demand of O2 by the                 (A) 10           (B) 25
         muscles                                      (C) 30           (D) 36
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96. For the synthesis of one molecule of          100. Match the correct combination
    glucose through Calvin cycle .........
    are required.                                     between A and B :
     (A) 6 CO + 30 ATP + 12 NADPH                                       (A)
     (B) 6 CO + 12 ATP
                                                      (1) Prokaryotic cells
     (C) 6 CO + 18 ATP + 12 NADPH
     (D) 6 CO + 18 ATP + 16 NADPH                     (2) Eukaryotic cells
97. The folding of sheet of cells, the                (3) Eukaryotic cells
    migration of cells and apoptosis are
    all mechanisms of :                               (4) Prokaryotic cells
    (A) cleavage pattern                                                (B)
    (B) pattern formation
    (C) morphogenesis                                 (i)   more than 10 micrometers and
    (D) differentiation                                     lack membrane surrounding
98. In Drosophila, the fate of early
                                                            every organells
    blastomeres       is   determined
    through :                                         (ii) more than 10 micrometers and
    (A) Autonomous specification
                                                            lack membrane around some
    (B) Conductional specification
    (C) Syncytial specification                             organelles
    (D) Maternal specification                        (iii) less than 10 micrometers and
99. How does P 53 prevent the
    unrestrained proliferation cells                        possess membrane around some
    leading to cancer ?                                     organelles
    (A) By preventing the proliferation
        of cells with damaged DNA                     (iv) less than 5 micrometers and
    (B) By acting as a transcription                        lack membrane around all
        factor
                                                            organells
     (C) By stimulating the synthesis of
                                                      (A) 1 and (ii)
         DNA repair enzymes which
         replace telomeres                            (B) 2 and (i)
     (D) By preventing cells from                     (C) 3 and (iii)
         triggering apoptosis
                                                      (D) 4 and (iv)

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ROUGH WORK




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Source: Savitribai Phule Pune University. Question paper published by Savitribai Phule Pune University.