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MH SET 2024: 7 April, Paper II, Life Sciences

  • Date: 7 April 2024
  • Paper code: APR-34224
  • Series: A
  • Language: Bilingual
  • 24 pages
MH SET 2024 question paper, 7 April 2024, Paper II, Life Sciences, page 1 of 24
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Test Booklet Code & Serial No.
                                                                                                                     A
                                                             LIFE SCIENCE
Signature and Name of Invigilator                                                         Seat No.
1. (Signature) .........................................
                                                                                                       (In figures as in Admit Card)
      (Name) ................................................
                                                                              Seat No. ..............................................................
2. (Signature) .........................................                                                (In words)
      (Name) ................................................                 OMR Sheet No.
APR - 34224                                                                                       (To be filled by the Candidate)
Time Allowed : 2 Hours]                                                                                [Maximum Marks : 200
Number of Pages in this Booklet : 24                                                    Number of Questions in this Booklet : 100
                      Instructions for the Candidates
1.         Write your Seat No. and OMR Sheet No. in the space provided             1.
           on the top of this page.
2.         This paper consists of 100 objective type questions. Each question
           will carry two marks. All questions of Paper II will be compulsory.     2.
3.         At the commencement of examination, the question booklet
           will be given to the student. In the first 5 minutes, you are           3.
           requested to open the booklet and compulsorily examine it as
           follows :
           (i)      To have access to the Question Booklet, tear off the
                    paper seal on the edge of this cover page. Do not accept                (i)
                    a booklet without sticker-seal or open booklet.
           (ii)     Tally the number of pages and number of questions in
                    the booklet with the information printed on the cover                   (ii)
                    page. Faulty booklets due to missing pages/questions
                    or questions repeated or not in serial order or any
                    other discrepancy should not be accepted and correct
                    booklet should be obtained from the invigilator within
                    the period of 5 minutes. Afterwards, neither the Question
                    Booklet will be replaced nor any extra time will be
                    given. The same may please be noted.
           (iii)    After this verification is over, the OMR Sheet Number
                                                                                            (iii)
                    should be entered on this Test Booklet.
4.         Each question has four alternative responses marked (A), (B),
           (C) and (D). You have to darken the circle as indicated below on        4.                      (A), (B), (C)    (D)
           the correct response against each item.
           Example : where (C) is the correct response.

                              A        B                 D                                           (C)
5.         Your responses to the items are to be indicated in the OMR                                      A        B               D
           Sheet given inside the Booklet only. If you mark at any place
           other than in the circle in the OMR Sheet, it will not be evaluated.    5.
6.         Read instructions given inside carefully.
7.         Rough Work is to be done at the end of this booklet.                    6.
8.         If you write your Name, Seat Number, Phone Number or put                7.
           any mark on any part of the OMR Sheet, except for the space
                                                                                   8.
           allotted for the relevant entries, which may disclose your
           identity, or use abusive language or employ any other unfair
           means, you will render yourself liable to disqualification.
9.         You have to return original OMR Sheet to the invigilator at the
           end of the examination compulsorily and must not carry it with          9.
           you outside the Examination Hall. You are, however, allowed
           to carry the Test Booklet and duplicate copy of OMR Sheet on
           conclusion of examination.
                                                                                   10.
10.        Use only Blue/Black Ball point pen.
                                                                                   11.
11.        Use of any calculator or log table, etc., is prohibited.
12.        There is no negative marking for incorrect answers.                     12.
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2
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APR - 34224/II—A
                                 Life Science
                                     Paper II
Time Allowed : 120 Minutes]                                       [Maximum Marks : 200
Note : This paper contains Hundred (100) multiple choice questions. Each question
        carrying Two (2) marks. Attempt All questions.

1.   Hydrogen bonds are present in water         3.   Which one of the following is not a
     structure. Presence of hydrogen                  part of cell theory ?
     bonds gives a characteristic property
                                                      (A) Organism(s) are made up of
     to water, which is :
                                                            cell(s)
     (A) High melting and high boiling
                                                      (B) Cells are functional unit(s) of
         points
                                                            multicellular organisms
     (B) High melting and low boiling
                                                      (C) Cells in a multicellular organism
         points
                                                            arise from preexisting cells
     (C) Low melting and high boiling
                                                      (D) Cells         in      a   multicellular
         points
                                                            organism are derived from non-
     (D) Low melting and low boiling
                                                            cells
         points
                                                 4.   Assembly of cytoplasmic micro-
2.   Which of the following membrane
                                                      tubule from the tubulin dimers is
     associated process involves the step
                                                      inhibited if the cell is treated
     of Clathrin coated vesicle formation
                                                      with ..................
     during its mechanism ?

     (A) Phagocytosis                                 (A) Streptomycin

     (B) Amino acid uptake                            (B) Calmodulin

     (C) Receptor mediated endocytosis                (C) Colchicine

     (D) Calcium uptake                               (D) Carbenicillin

                                             3                                             [P.T.O.
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5.   Prokaryotes may be characterised            7.   The first chromosomal linkage map

     by :                                             for five genes on the X chromosome

     (A) Presence of nucleus or nucleoid              of Drosophilla was constructed by :

     (B) Absence of DNA                               (A) S. Benzer

                                                      (B) T.H. Morgan
     (C) Absence        of   membrane

            surrounding organells                     (C) A.H. Sturtevant

     (D) Presence of membrane around                  (D) G.J. Mendel

            RNA                                  8.   A chromosomal site at which a group

6.   The following are the characteristics            of genes affecting quantitative traits

     of which type of transposable                    are located is called as :

     element ?                                        (A) Qualitative trait locus

     Simplest transposable element found              (B) Quantitative trait locus

     in bacteria that encode transposase,             (C) Multiple allele locus

     with less than 5 kb size and with                (D) Dominant locus
     terminal inverted repeats that can
                                                 9.   In prion disease, classically, the :
     transfer DNA directly is :
                                                      (A) Liver becomes excessively
     (A) Composite transposons
                                                          enlarged

     (B) Retrotransposons                             (B) Liver becomes sponge like

     (C) IS element                                   (C) Brain ventricles are squeezed

     (D) Tn3-like elements                            (D) Brain becomes sponge like

                                             4
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10. Which one of the following is not a        13. Taxonomic hierarchy refers to :
    diversity index of living organism ?
                                                   (A) Classification of species based
    (A) Shannon index
                                                       on fossil record
    (B) Simpson index

    (C) Berger-Parker index                        (B) A list of taxonomists worked on

    (D) MPN index                                      taxonomy of a species

11. Articulation of both the jaws with
                                                   (C) A group of taxonomists who
    skull is termed as Jaw suspension.
                                                       decide nomenclature of animals
    One of the following types is

    observed in the teleost fishes :                   and plants

    (A) Craniostylic                               (D) Stepswise arrangement of all

    (B) Autostylic                                     categories for classification of
    (C) Holostylic
                                                       animals and plants
    (D) Hyostylic
                                               14. Mycoplasmas, rickettsiae, and
12. In the representatives of order
    Cestoda, the mature proglottids get            chlamydiae are :
    separated from main body by a
                                                   (A) Types of fungi
    process known as :

    (A) Apoptosis                                  (B) Small bacteria
    (B) Apolysis
                                                   (C) Species of protozoa
    (C) Homolysis

    (D) Genolysis                                  (D) Forms of viruses

                                           5                                    [P.T.O.
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15. When biological oxygen demand             18. What largest bacterium of > 600     m
    becomes very high ?
                                                   size is known to inhabit the gut of
    (A) The water becomes suitable for
                                                   Acantharus nigrofuscus ?
        growth of aerobic microbes

    (B) The amount of dissolved oxygen             (A) Vibrio fischeri
        increases
                                                   (B) Spirillum volutans
    (C) The water becomes anaerobic
                                                   (C) Epulopiscium fishelsoni
    (D) Both concentration of microbes
        and dissolved oxygen decreases             (D) Borrelia burgdorferi
16. Which one of the following extra
                                              19. Heliophytes are the plants :
    embryonic membrane found as
    unique feature in terrestrial                  (A) Growing under shade
    vertebrates only ?
                                                   (B) Growing under direct sunlight
    (A) Yolk sac
                                                   (C) Growing under waterlogged
    (B) Chorion
                                                          conditions
    (C) Allantois
                                                   (D) Growing          under    saline
    (D) Amnion
                                                          conditions
17. Since humans are having such a
    notable impact on the Earth and its       20. The largest ‘carbon sink’ on the earth
    life—a new, youngest epoch of the
                                                   is :
    quaternary period is termed as :
                                                   (A) Forests
    (A) The Holocene

    (B) The Paleocene                              (B) Soils

    (C) The Anthropocene                           (C) Oceans

    (D) The Eocene                                 (D) Animals

                                          6
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21. Nomenclature is governed by                24. Cridu chat syndrome is caused due
    certain universal rules. Which one
                                                   to which of the following ?
    of the following is contrary to the
    rules of nomenclature ?                        (A) Deletion of short arm of

    (A) The first word represents genus                chromosome no. 5
        and second is a specific epithet
                                                   (B) Translocation of long arm of
    (B) The names are written in Latin
                                                       chromosome no. 5
        and italicised

    (C) Biological names can be written            (C) Duplication of short arm of

        in any language                                chromosome no. 5
    (D) When written by hand, names
                                                   (D) Inversion of short arm of
        are to be underlined
                                                       chromosome no. 5
22. Which among the following is
    functionally more diverse ?                25. If the genotypes of a husband and
    (A) DNA
                                                   a wife are IAIB, how many different
    (B) RNA
                                                   genotypes and phenotypes are
    (C) Protein
                                                   possible among the blood types of
    (D) Lipid

23. River blindness disease occurs                 their children.

    due to :                                       (A) 2 genotypes : 3 phenotypes
    (A) Loa loa
                                                   (B) 3 genotypes : 4 phenotypes
    (B) Mansonella perstans
                                                   (C) 4 genotypes : 3 phenotypes
    (C) Mansonella streptocerca

    (D) Onchocerca volvulus                        (D) 4 genotypes : 4 phenotypes

                                           7                                     [P.T.O.
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26. The maternal characteristics are
                                                    29. In addition to serving as the
    inherited through cytoplasmic
    inheritance also. One of the following             building blocks for nucleic acid,
    organell is involved in :
                                                       nucleotides have many functions.
     (A) Mitochondria
                                                       Which of the following is not a
     (B) Golgi body
     (C) Lysosomes                                     function of a nucleotide ?

     (D) Endoplasmic reticulum                         (A) They work as carriers of energy
27. Trisomy of chromosome no. 21 is :
     (A) Edwards syndrome                              (B) They are serving as secondary

     (B) Klinefelter syndrome                              messengers in cells
     (C) Down syndrome
                                                       (C) They are the components of
     (D) Patau syndrome
28. A bacterial strain that is lys+ his+                   coenzymes
     val+ is used as a donor, and another
     strain that is lys– his– val– as the              (D) They provide electrons to the
     recipient for setting up an
                                                           ETC
     experiment on transformation.
     Initial transformants were isolated            30. A DNA sample contains 30%
     on a minimal medium with
     supplemented with lysine and                      adenine on molar basis. What will
     valine. Which of the following                    be the percentage of cytosine ?
     maximum genotypes will grow on
     this medium ?                                     (A) 30%
     (A) lys– his+ val+; lys+ his+ val–; lys+
         his+ val+; lys– his+ val–                     (B) 20%

     (B) lys+ his+ val+; lys– his– val+
                                                       (C) 40%
     (C) lys– his– val– only
     (D) lys+ his– val+ only                           (D) 60%

                                                8
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31. Which of the following would               33. Which chiral angle in the peptide

                                                   backbone       does   not   undergo
    contribute to intrinsic fluorescence
                                                   rotation ?
    in a protein ?
                                                   (A)   (Phi)
    (A) Aromatic amino acids
                                                   (B)    (Psi)
    (B) Charged amino acids                        (C)    (Chi)

    (C) Branched chain amino acids                 (D)    (Omega)

    (D) Disulfide bonds                        34. Efficiency of enzyme can be better
                                                   measured in terms of :
32. The screw sense of DNA can be right
                                                   (A) Km
    handed or left handed. Which of the
                                                   (B) Km/Vmax
    following statements is correct with
                                                   (C) Kcat
    respect to the screw sense of A, B
                                                   (D) Kcat/Km
    and Z type of DNA ?
                                               35. What is the resultant pH of a
    (A) A and Z both right handed                  phosphate buffer made by mixing
                                                   0.2 M NaH2PO4 and 0.2 M Na2HPO4 ?
    (B) A and B both right handed
                                                   (pKa = 6.86)
    (C) A left handed and B right
                                                   (A) 5.86
        handed
                                                   (B) 6.86
    (D) A right handed and B left
                                                   (C) 7.86
        handed
                                                   (D) 7.00

                                           9                                    [P.T.O.
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36. A protein mixture contains three                38. First fossil record of vascular plants

    polypeptides A, B and C, whose                       appeared in the .................. period.

    masses are 63, 28 and 79 kDa with
                                                         (A) Silurian
    pI values of 6.5, 7.0 and 8.0,
                                                         (B) Jurassic
    respectively, were subjected to

    standard reducing SDS-PAGE. The                      (C) Triassic

    order of their separation from top to
                                                         (D) Cambrian
    bottom would be :
                                                    39. Inclusive fitness refers to .............
    (A) A, B and C
                                                         (A) Reproductive success of an
    (B) C, B and A
                                                              individual
    (C) A, C and B
                                                         (B) Reproductive success of an
    (D) C, A and B
                                                              individual along with its
37. A geographically variable species                         neighbour’s         reproductive
    often divided into many subspecies
                                                              success
    is referred to as ......................
                                                         (C) Reproductive success of an
    (A) Monotypic species
                                                              individual along with its
    (B) Sister species
                                                              relatives’ reproductive success

    (C) Sibling species
                                                         (D) Reproductive success of an

    (D) Polytypic species                                     individual and its partners

                                               10
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40. In a classical experiment, a standard        42. Sarich      and   Wilson    (1967)
    is usesd to :
                                                     demonstrated that human, Gorilla
    (A) Add background noise                         and Chimpanzee were genetically
    (B) Record the absolute value of a               equidistant and distinct for Orang-
         signal
                                                     utan and the divergence time is
    (C) Compare and eliminate non-                   approximately :
         specific background noise
                                                     (A) 30 mya
    (D) Record the non-specific error in
         the experiment                              (B) 05 mya

41. Why sexual selection can lead to                 (C) 10 mya

    extreme phenotypes ?
                                                     (D) 100 mya
    (A) Because the extreme phenotype
                                                 43. Beaker ‘A’ has 100 ml of some fluid
         incurs lower costs than the
                                                     at 80°C. Beaker B contains the some
         mean train in the population
                                                     fluid 200 ml at 20ºC. If both the
    (B) Because the partner quickly
                                                     fluids are mixed, what would be the
         learns and favours new images
                                                     temperature of the resultant
    (C) Because a positive feedback
                                                     mixture ?
         exists     between   the   gene
         favouring the trait and the gene            (A) 25ºC
         coding for it
                                                     (B) 65ºC
    (D) Because a negative feedback
                                                     (C) 40ºC
         exists between the trait and the

         risk of predation                           (D) 50ºC

                                            11                                   [P.T.O.
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44. With the advent of Remote Sensing              46. What will be the radioactivity of
    and Geographical Information                       125I labelled 2 mCi thyroxine after

    System, the city planners have                     4 generations (t½ = 60 days) :
    begun to use the Indian satellite
                                                       (A) 0.25 mCi
    data. Which one of the following
    satellite data are useful for such                 (B) 0.125 mCi
    tasks ?                                            (C) 0.125 µCi
    (A) CARTOSAT                                       (D) 1 mCi
    (B) LANDSAT
                                                   47. Among the different types of
    (C) OCEANSAT                                       phytoremediation   .............. is the
    (D) RESOURCESAT                                    process in which plants limit
                                                       contaminated soil movement and
45. Which of the following statements
                                                       migration.
    is not true about phase contract
    microscopy ?                                       (A) Phytostabilization

    (A) It is a modified version of the                (B) Phytotransformation
        bright field microscope that is
                                                       (C) Phytodegradation
        fitted with a condenser (annular
        ring) and objective (phase plate)              (D) Phytoextraction

    (B) It uses a special condenser and            48. Which of the following proteins
        objective that accentuate small                helps to maintain and stabilizes
        differences in the refractive                  protein tertiary structure during
        index of various structures                    temperature stress in plants ?
        within the organism
                                                       (A) Defensins
    (C) It can be used to observe living
                                                       (B) Thionins
        cells in their natural state
                                                       (C) Late embryogenesis abundant
    (D) It uses laser light to obtain focal
                                                           (LEA)
        level    sections    through     a
        specimen                                       (D) Osmotin
                                              12
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49. Enzyme labelled antibodies are not            51. Amplification of a DNA fragment by

    generally used for which of the                   PLR requires primers.

    following techniques ?                            Which of the following statements

                                                      are correct for primers ?
    (A) FACS
                                                      (i)   Primers with hairpin structure
    (B) Immunohistochemistry
                                                            formation are not desirable
    (C) ELISA
                                                      (ii) Primer sequence should not

    (D) Western blot                                        have long runs (>3) of a single

                                                            nucleotide
50. In   watermelons,        to   induce

                                                      (iii) GC content of the primer should
    seedlessness in triploid population,
                                                            be less than 20%
    which of the following strategies is
                                                      (iv) Both the forward and reverse
    useful ?
                                                            primers      must    have    high
    (A) Self-pollinate resistant triploids
                                                            percentage           of      base

    (B) Cross unrelated triploids                           complementarities

    (C) Select for unreduced gametes in               (A) (i), (ii) and (iii)

         triploids                                    (B) (ii), (iii) and (iv)

    (D) Cross tetraploids with diploids               (C) (i) and (ii)

         to produce triploids                         (D) (iii) and (iv)

                                             13                                         [P.T.O.
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52. When subcultured into fresh                  54. Which one of the following is not a
    medium, a bacterium grows with a
                                                     fluorophore ?
    lag phase of 2 hours followed by log
                                                     (A) Acridine orange
    phase and a stationary phase. If the

    bacterium was treated with ethidium              (B) Acrylamide

    bromide for 3 hours in all the phases
                                                     (C) Quinacrine
    of growth to cure a plasmid, it is

    more likely to lose the plasmid                  (D) Ethidium bromide

    in :                                         55. Which of the following best describes

    (A) Early stationary phase                       principle of western blotting

    (B) Late stationary phase                        technique ?

    (C) Logarithmic phase                            (A) A means of separation of

    (D) Lag phase                                         restriction fragments on the

53. The free hydroxyl groups present on                   basis of size
    either end of chemically synthesized.
                                                     (B) It is based on attraction to a
    Oligonucleotides are 5'–phosphory-
                                                          specific chemical group
    lated with ATP by the enzyme :

    (A) Polynucleotide phosphatase                   (C) The proteins have a net charge

                                                          zero at a particular pH
    (B) Polynucleotide phosphorylase

    (C) Polynucleotide ATPase                        (D) It is an immunoassay technique

    (D) Polynucleotide kinase                             preceded by electrophoresis

                                            14
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56. Which of the following is resulted                59. The hormone auxin was first
    due to photorespiration reaction
                                                          discovered in :
    catalysed by oxygenase activity of
    rubisco ?                                             (A) Mustard

    (A) 3-phosphoglycerate only                           (B) Pea
    (B) 2-phosphoglycolate only
                                                          (C) Oats
    (C) Fructose 6-phosphate
                                                          (D) Rice
    (D) 3-phosphoglycerate                and
                                                      60. How many times more energy gained
         2-phosphoglycolate
                                                          in aerobic respiration over
57. Mutation in ACC synthase enzyme
    will inhibit synthesis of ................            anaerobic respiration ?

    (A) Gibberellins                                      (A) 8

    (B) Salicyclic acid                                   (B) 12

    (C) Ethylene                                          (C) 18
    (D) Auxin                                             (D) 32
58. Which of the following phytohormone               61. Which of the following is NOT
    accumulates        during      Systemic
                                                          involved in electron transport during
    Acquired Resistance (SAR) in
    plants ?                                              Photosystem I and II ?

    (A) Salicylic acid                                    (A) Ferredoxin

    (B) Jasmonic acid                                     (B) Plastocyanin

    (C) Abscisic acid                                     (C) Cytochrome b6f complex

    (D) Ethylene                                          (D) Cytochrome oxidase

                                                 15                                    [P.T.O.
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62. The treatment of abscisic acid is            65. What kind of microbes grow best at

    associated with .....................            higher CO2 tension (~ 10%) than are

    (A) Internode elongation                         normally present in the atmosphere ?

    (B) Expansion of lead area                       (A) Microaerophilic microorganisms

    (C) Closure of stomata                           (B) Capnophilic microorganisms

    (D) Axillary root elongation                     (C) Aerotolerant          anaerobic

63. Action potential is generated due                    microorganisms

    to :                                             (D) Obligate              anaerobic

    (A) Influx of Na+ and efflux of K+                   microorganisms


    (B) Influx of Ca2+ and efflux of K+          66. Which free living microorganisms

                                                     occupy a niche to feed primarily on
    (C) Influx of Na+ and efflux of Ca2+
                                                     organic    detritus   from     dead
    (D) Influx of K+ and efflux of Na+
                                                     organisms and unable to adapt to

64. Hookworm infection can lead to                   the body of live host ?

    deficiency of :
                                                     (A) Obligate saprobic microorganisms

    (A) Vitamin B12
                                                     (B) Parasitic microorganisms

    (B) Iron
                                                     (C) Facultative           parasitic

    (C) Vitamin B6                                       microorganisms

    (D) Folic acid                                   (D) Auxotrophic microorganisms

                                            16
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67. The DNA of each chromosome                 70. The triple helix domain of collagen
    occupies a defined volume of the
                                                   consists of repeats of the X-Y-Z
    nucleus and only overlaps with its
    immediate neighbours is called as :            amino acids. The amino acid present
    (A) Chromosome territories
                                                   at ‘X’ position is required in every
    (B) Nuclear scaffolds
    (C) Nucleosome assembly                        third position in order for the

    (D) Chromatin                                  polypeptide chain is :
68. Amphibians contain 30X more DNA
                                                   (A) Lysine
    than human beings. However
    human beings are more complex                  (B) Proline
    than amphibians. This lack of
    correlation is called as :                     (C) Hydroxy proline

    (A) Species specificity                        (D) Glycine
    (B) C-value paradox
                                               71. Which DNA binding domain is
    (C) D-value paradox
    (D) P-value paradox                            present in steroid hormone receptors
69. Which one of the following is not
                                                   family    of   ligand     inducible
    true in relation to eukaryotic gene
    expression ?                                   transcription factors ?

    (A) RNA POl I synthesizes pre-
                                                   (A) Helix-loop-helix
         RNA
    (B) RNA POl II synthesizes RNA                 (B) Zinc fingers

    (C) RNA POl III synthesizes tRNA
                                                   (C) Helix-turn-helix
    (D) All three polymerase contains
         ',   ,    and   subunits.                 (D) Leucine zipper

                                          17                                    [P.T.O.
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72. Which of the following elongation           75. Identify the enzymes involved in

    factor is called as translocase ?               DNA replication for their function :

    (A) EF-G
                                                               (Enzyme)
    (B) EF-2
                                                    (P) DNA polymerase I
    (C) EF-G and EF-2
                                                    (Q) Primase
    (D) EF-Tu and EF-Ts

73. Which of the following post-                    (R) Helicase

    translational modification is not               (S) Gyrase
    related with epigenetic regulation ?
                                                               (Funtion)
    (A) Histone acetylation
                                                    (1) Unzipping the DNA helix
    (B) Sumoylation

    (C) Ubiquitination                              (2) Supercoiling of DNA

    (D) DNA methylation                             (3) Remove primer and close gaps

74. The disease which arises because of
                                                    (4) Synthesize RNA primer
    aberrant splicing is :
                                                    (A) (P)-(2),(Q)-(3),(R)-(4),(S)-(1)
    (A) Huntington’s disease
                                                    (B) (P)-(3),(Q)-(4),(R)-(1),(S)-(2)
    (B) Cystic fibrosis

    (C) Sickle cell anemia                          (C) (P)-(1),(Q)-(4),(R)-(2),(S)-(3)

    (D) Thalassemia                                 (D) (P)-(3),(Q)-(1),(R)-(2),(S)-(4)

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76. (I) The 3' to 5' exonuclease activity
                                                    78. Which of the following statements
         of eukaryotic DNA polymerase
         operates in reverse direction of               about apoptosis is fasle ?
         DNA synthesis and participate
         in fidelity of replication.                    (A) Cell shrinks

    (II) The ability of DNA polymerase                  (B) Chromatin condenses
         to extend a primer only in 5' to
         3' direction appears to make                   (C) Cell contents are leaked
         replication     a   complicated
         process, it is necessary for proof-            (D) Apoptotic bodies are formed,

         reading of duplicated DNA.
                                                            which are phagocytosed by
    Choose the correct answer :
                                                            macrophages
    (A) (I) is correct, (II) is wrong

    (B) (II) is correct, (I) is wrong               79. Which of the following signalling
    (C) Both (I) and (II) are correct
                                                        molecules plays a key role in the
    (D) Both (I) and (II) are wrong

77. Which of the following is a wrong                   patterning of neural tube along its
    statement in SOS repair system ?
                                                        anterior-posterior axis ?
    (A) Lex A shows autorepression of
         lex A                                          (A) Wnt4
    (B) Lex A shows repression of rec A
                                                        (B) BMP4
    (C) Negative regulation of Lex A
         blocks the SOS repair
                                                        (C) FGF4
    (D) Rec      A    shows      negative
         regulation of lex A                            (D) Retinoic acid

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80. If you compare the B cell epitope             82. Which of the following molecules
    against T cell epitope :                          acts       as   a   general      adhesive

    (A) B cell epitopes are based more                connecting one cell to another and
                                                      cells to other substrates ?
        on primary sequence of protein
        antigen                                       (A) Fibronectin
                                                      (B) Heparin sulphate
    (B) B cell epitopes are based more
                                                      (C) Collagen
        on nature conformation of
        protein antigen                               (D) Laminin
                                                  83. Formation and migration of epiblast
    (C) B cell epitopes are based more
                                                      as     a    sheet    of   cells     during
        on presentation of antigen by
                                                      gastrulation in zebra fish requires
        MHC molecule
                                                      the expression of ....................
    (D) B cell epitopes are of continuous
                                                      (A) P-cadherins
        epitopes than the B cell epitope
                                                      (B) R-cadherins
81. Mark the correct statement for
                                                      (C) N-cadherins
    antigenicity of molecule :
                                                      (D) E-cadherins
    (A) Antigenicity is the ability of the
                                                  84. Which of the following groups of
        molecule to provocate immune
                                                      transcription factors (TFs) is
        response in the body
                                                      responsible for maintaining the
    (B) Antigenicity refers to the                    pluripotency of stem cells ?
        binding ability of Antibody to                (A) Oct 4, Nanog and Stat 3
        its antigen                                   (B) Oct 4, Nanog and SOX 2
    (C) Antigenicity                 and              (C) Eomesodermin, Cdx 2 and
        immunogenicity are synonyms                        SOX 2
    (D) All antigens are immunogens                   (D) Cdx 2, Nanog and SOX 2

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85. Yersinia pestis is the causative agent                 88. Which of the following is necessary
     for ................                                      for the development of epididymis in
     (A) Gas gangrene                                          mammals ?

     (B) Tularemia                                             (A) Dihydrotestosterone
     (C) Lyme disease                                          (B) Methyl testosterone
     (D) Plague                                                (C) Testosterone
86. Pseudohermaphroditism                    is   a            (D) Androsterone
     condition in which the individual is
                                                           89. The mid-blastula transition is the
     insensitive to ....................
                                                               point in the development when ..........
     (A) Androgen
                                                               (A) Translation of maternal mRNA
     (B) Estrogen                                                  is initiated

     (C) Progesterone                                          (B) Cell determination is fixed

     (D) Corticosterone                                        (C) Cell-division in the zygote

87. In plants, when the apical cell of the                         begins

     2-celled           pro-embryo         divides             (D) Transcription of zygotic genes
     longitudinally and further the basal                          begins
     cell plays only a minor role or none                  90. In the chick limb, the signal for
     in the development of the embryo                          condensation of mesenchymal cells
     proper then the embryo is ............                    to give rise to cartilage comes from
     type.                                                     the appearance of :
     (A) Asterad                                               (A) N-cadherins

     (B) Onagrad                                               (B) E-cadherins

     (C) Solanad                                               (C) C-cadherins

     (D) Chenopodial                                           (D) B-cadherins

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91. Which of the following is not a              94. Increased muscle activity will
    property of stem cells ?                         increase generation of lactic acid. In
    (A) Ability to self-renew                        this condition, blood coming from the
                                                     lungs to the muscles, would show :
    (B) Ability to differentiate into
                                                      (A) Increased O 2 release from
        different types of cells                          haemoglobin
    (C) They are unspecialised cells                  (B) Decreased O 2 release from
        with cell markers                                 haemoglobin

    (D) They are actively dividing cells              (C) No change in O 2 release
                                                          property
        with cell marker changes
                                                      (D) Increased degradation         of
92. Which of the following proteins acts                  haemoglobin
    as a death receptor that triggers the
                                                 95. The capability of vertebrate kidney
    extrinsic pathway of apoptosis ?                 and produce hypertonic urine is a
    (A) Fas ligand                                   function of :
                                                      (A) Reduced filtration at the
    (B) FADD
                                                          glomerulus
    (C) FaS                                           (B) Increased reabsorption at
    (D) Procaspase 9                                      Bowman’s capsule
                                                      (C) The loop of Henle
93. With reference to normal ECG, the
    T-wave is :                                       (D) Addition of waste molecules in
                                                          the Bowman’s capsule
    (A) Negative in all standard bipolar         96. For long distance runner, the muscle
        limb leads recording                         needs increased O2 supply. At the
    (B) Caused by repolorization of                  muscle, this is formed by :
        apex and outer surfaces of the                (A) Increased and frequent muscle
        ventricles                                        contraction
                                                      (B) Increased demand made by the
    (C) Abnormal when          normal                     muscles
        sequence of depolarization does
                                                      (C) Increased squeezing of the
        not occur                                         muscles
    (D) Caused by depolarization of the               (D) Increased accumulation of lactic
         septum and the ventricles                        acid causing demand blood pH

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97. Which of the following heat shock            99. Match the following product/process

    proteins has both protein folding and            to the microorganism involved :

    degradation activities ?                               Product/Process

    (A) HSP 60                                       (L) Biopol

                                                     (M) Biopesticide
    (B) HSP 70
                                                     (N) Bioleaching
    (C) HSP 90
                                                     (O) Bioremediation of oil
    (D) HSP 100
                                                         Microorganism
98. The sequential order of various
                                                     (1) Thiobacillus ferroxidans
    stages of a fermentation process
                                                     (2) Pseudomonas putida
    are :
                                                     (3) Bacillus sphaericus
    (A) Fermentation, removal of waste,
        inoculation,      downstream                 (4) Alcaligenes eutrophus

        processing                                   (A) (L)-(1),(M)-(4),(N)-(2),(O)-(3)

    (B) Inoculation,      downstream                 (B) (L)-(2),(M)-(1),(N)-(3),(O)-(4)

        processing,     fermentation,                (C) (L)-(3),(M)-(1),(N)-(2),(O)-(4)

        removal of waste                             (D) (L)(-4),(M)-(3),(N)-(1),(O)-(2)

    (C) Inoculation,    fermentation,            100. In golden rice, the gene phytoene
        downstream          processing,              desaturase (crtl) was obtained from :

        removal of waste                             (A) Narcissus species

    (D) Removal of waste, inoculation,               (B) Erwinia uredovera

        fermentation, downstream                     (C) Zea mays
        processing                                   (D) Oryza sativa

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Source: Savitribai Phule Pune University. Question paper published by Savitribai Phule Pune University.