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TS SET 2012: Paper II, Life Sciences

  • Paper code: 09
  • Language: Bilingual
  • 16 pages
TS SET 2012 question paper, TS SET 2012, Paper II, Life Sciences, page 1 of 16
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Test Paper                          : II                                                        Test Booklet Serial No. : ______________________
                                                                                                OMR Sheet No. : ________________________________
Test Subject                        : LIFE SCIENCES
                                                                                                Hall Ticket No.
Test Subject Code :                           A-09-02
                                                                                                                                (Figures as per admission card)

Name & Signature of Invigilator

Name               : ____________________________________                                       Signature : ___________________________________
                                                                       Paper   : II
                                                                       Subject : LIFE SCIENCES
Time : 1 Hour 15 Minutes                                                                                                                        Maximum Marks : 100
Number of Pages in this Booklet : 16                                                                           Number of Questions in this Booklet : 50
                  Instructions for the Candidates                                                                              A¿æýÅÆæÿ$¦ËMæü$ çÜ*^èþ¯èþË$
 1. Write your Hall Ticket Number in the space provided on the top                              1. D ç³#r ò³O ¿êVæü ÌZ CÐèþÓºyìþ¯èþ çÜ¦Ë ÌZ Ò$ çà̌ý sìýMðüsŒý ¯èþ ºÆæÿ$ Æ>Äæý$ yìþ.
    of this page.                                                                               2. D {ç³Ôèý² ç³{™èþÐèþ$$ Äæý*¿ñýO ºçßý$âñýO_eMæü {ç³Ôèý²Ë¯èþ$ MæüÍW E ¨.
 2. This paper consists of fifty multiple-choice type of questions.                             3. ç³È„æü {´ëÆæÿ ¿æýÐèþ$$¯èþ D {ç³Ôé²ç³{™èþÐèþ$$ Ò$Mæü$ CÐèþÓºyæþ$™èþ$ ¨. Ððþ$$§æþsìý I§æþ$
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           discrepancy should be got replaced immediately by a                             Ðèþ sìý §øçÙç³NǙèþÐðþ$O¯èþ {ç³Ôèý² ç³{™é°² Ððþ r¯óþ Ððþ$$§æþsìý I§æþ$ °Ñ$ÚëÌZÏ ç³È„>
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     (iii) After this verification is over, the Test Booklet Number                        A§óþÑ«§æþ V> OMR ç³{™èþÐèþ$$ çÜ Qůèþ$ D {ç³Ôé²ç³{™èþÐèþ$$ ò³O °ÇªçÙtt çÜ¦Ë ÌZ Æ>Äæý$ÐèþÌñý¯èþ$.
           should be entered in the OMR Sheet and the OMR Sheet           4. {糆 {ç³Ôèý²Mæü$ ¯éË$Væü$ {糙éÅÐèþ*²Äæý$ {糆çܵ §æþ¯èþË$ (A), (B), (C) Ðèþ$ÇÄæý$$ (D)
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    correct response against each item.                                        ç³NÇ ^éÍ.
    Example : A            B      C      D                                     E§éçßýÆæÿ×ý :                         A             B     C      D
    where (C) is the correct response.                                         (C)     ç Ü  Æð ÿ O ¯ è þ {ç ³ †ç Ü µ §æ þ ¯è þ AÆÿ$$™ó þ
                                                                          5. {ç³Ôèý²ËMæü$ {糆çܵ §æþ¯èþ˯èþ$ D {ç³Ôèý²ç³{™èþÐèþ$$™ø CÐèþÓºyìþ¯èþ OMR ç³{™èþÐèþ$$ ò³O¯èþ
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 8. If you write your name or put any mark on any part of the OMR 8. OMR ç³{™èþÐèþ$$ ò³O °È~™èþ çÜ¦Ë ÌZ çÜ*_ ^èþÐèþËíܯèþ ÑÐèþÆ>Ë$ ™èþí³µ _ C™èþÆæÿ çÜ¦Ë ÌZ
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    liable to disqualification.                                           9. çç³È„æü ç³NÆæÿ¢Æÿ$$¯èþ ™èþÆ>әèþ Ò$ {ç³Ôèý²ç³{™é°² Ðèþ$ÇÄæý$$ OMR ç³{™é°² ™èþç³µ°çÜÇV>
 9. You have to return the test question booklet and OMR Answer
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    and must not carry it with you outside the Examination Hall.         10.   ±Í/¯è     þËÏ Ææÿ Væü$ »ê̌ý ´ëÆÿ$$ sŒý ò³¯Œþ Ðèþ*{™èþÐóþ$ Eç³Äñý*W ^éÍ.
10. Use only Blue/Black Ball point pen.                                  11.   ÌêVæ üÇ£æ  þЌþ$ sôýº$̌ýÞ, M>ÅÍMæü$ÅÌôýrƊÿË$, GË[M>t°MŠü ç³ÇMæüÆ>Ë$ Ððþ$$§æþËVæü$¯èþÑ ç³È„æüVæü¨ÌZ
11. Use of any calculator or log table etc., is prohibited.                  Eç³Äñý*W ^èþyæþ °õÙ«§æþ .
12. There is no negative marks for incorrect answers.                    12. ™èþ糚 çÜÐèþ*«§é¯éËMæü$ Ðèþ*Ææÿ$PË ™èþWY ç³# Ìôý§æþ$.
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                                        LIFE SCIENCES

                                          Paper – II




 1. Eukaryotic mRNA can be separated from             4. Which of the following organellae does

      the total RNA by                                  not carry out transcription ?

       (A) Size Exclusion chromatography                 (A) Nucleus

       (B) Ion-Exchange chromatography                   (B) Peroxisome

      (C) Affinity chromatography                        (C) Chloroplast

      (D) Partition chromatography                       (D) Mitochondrian


 2. Which of the following involves the               5. Given below are two statements

      combining of two cells without cell walls
                                                        Assertion (A) : Hexokinase and
      from different plants ?
                                                                         Glucokinase have low
       (A) Clonal propagation
                                                                         and high k m towards
       (B) Hybridization
                                                                         glucose respectively.
      (C) Protoplast fusion
                                                        Reason (R) : Glucokinase operates
      (D) Mutant selection
                                                                         under    high     glucose

 3. Non-polar amino acid residues are found                              concentratian only .

      mostly                                            Which of these statements are correct ?

       (A) In the core of proteins                       (A) A is correct but R is wrong

       (B) On the surface of proteins                    (B) R is correct but A is wrong

      (C) On alpha helix                                 (C) Both A and R are correct

      (D) In no specific region                          (D) Both A and R are wrong


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 6. Given below are two statements. One                  8. Match the following

      labelled as Assertion (A) and the other           I. Nuclear Magnetic Resonance   1. Microwaves

      labelled as Reason (R)                           II. Electron Spin Resonance      2. Radiowaves

                                                       III. Raman spectroscopy          3. UV/Visible light
      Assertion (A) : Protooncogenes        are        IV. Spectrophotometry            4. Infrared waves
                      found in most of the                             I    II    III   IV
                      animal cells.                            (A)     4    3     2     1
      Reason (R) : They are related to viral                   (B)     1    2     4     3
                      oncogenes.                              (C)      2    1     4     3
                                                              (D)      2    3     4     1
      In the context of these statements which
      one of the following is correct ?                  9.    Match the following

       (A) A is correct but R is wrong                  I. Bt cotton             1. Improved shelf life

       (B) Both A and R are correct                    II. Flavr Savr Tomato     2. Improved nutritional quality

                                                       III. Roundup Ready        3. Pest resistance
      (C) A is wrong but R is correct
                                                           Sorghum
      (D) Both A and R are wrong
                                                       IV. Golden Yellow Rice    4. Herbicide tolerance

 7. Given below are two statements                                     I    II    III   IV
                                                               (A)     4    2     1     3
      Assertion (A) : All eukaryotic mRNAs are
                                                               (B)     3    1     4     2
                      capped at 5′ end
                                                              (C)      4    2     3     1
      Reason (R) : 5′ cap is not essential for
                                                              (D)      3    2     1     4
                      efficient mRNA translation
                                                        10. Viruses that persist in the cell and cause
      Which of these statements are correct ?                 recurrent disease are called
       (A) A is correct, R is wrong                            (A) Oncogenic viruses
       (B) Both A and R are correct                            (B) Latent viruses
      (C) A is wrong R is correct                             (C) Cytopathic viruses

      (D) Both A and R are wrong                              (D) Resistant viruses

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11. Assertion (A) : Indirect somatic                         13. Match the following
                             embryogenesis,                  I. Pyridoxal phosphate         1. Vitamin B
                                                                                                           1

                             embryos are developed          II. Niacin                      2. Vitamin B
                                                                                                           6

                             without going through          III. Thiamin pyrophosphate      3. Vitamin B2

                             callus formation.              IV. Flavin nucleotides          4. Vitamin B
                                                                                                           3

                                                                             I       II    III   IV
      Reason (R)            : This is possible due to
                                                                   (A)       1       2     3     4
                             the presence of pre-
                                                                   (B)       2       4     1     3
                             embryonically
                                                                   (C)       4       3     2     1
                             determined cells.                     (D)       3       4     1     2
       (A) Both A and R are true but R is not
                                                             14. The protein structure is stabilized by
           correct reason for A
                                                                    I. Hydrogen bonds
       (B) A is false but R is true                                 II. Disulphide bonds
      (C) A is true but R is false                                 III. Glycolidic bonds

      (D) Both A and R are true and R is the                       IV. Hydrophobic interactions

           correct reason for A                                    (A) I and II are correct
                                                                   (B) II, III and IV are correct
12. In complement cascade the complement                           (C) I and IV are correct
      1 activate as follows                                        (D) I, II and IV are correct

        I. C1q                                               15. Two dimensional electrophoresis involves
       II. C1r                                                     (A) SDS-PAGE in 1st dimension and IEF

       III. C1s                                                          in 2nd dimension
                                                                   (B) IEF in 1st dimension and SDS-PAGE
      IV. C1d
                                                                         in 2nd dimension
       (A) I, II, III, IV
                                                                   (C) IEF in 1st dimension and PFGE in
       (B) II, III, IV, I                                                2nd dimension
                                                                                     st
      (C) III, IV, II, I                                           (D) IEF in 1           dimension and TLC in

      (D) IV, III, II, I                                                 2 nd dimension


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16. Electron Transport chain contains the                18. Give the correct sequence of following
      following components :
                                                            steps used in Southern hybridization
        I. Cytochrome C-oxidase

       II. Succinate/COQ oxidoreductase                     1. Blotting membrane

       III. NADH : COQ oxidoreductase                       2. Restriction digestion
      IV. Coenzyme Q : cytochrome
                                                            3. Detection
           oxidoreductase

                                                            4. Separation by electrophoresis
      Choose correct one of following
      sequences                                             Choose the correct one
       (A) III, II, IV, I
                                                             (A) 4, 1, 2, 3
       (B) II, III, IV, I

      (C) I, IV, III, II                                     (B) 2, 4, 1, 3

      (D) IV, III, II, I
                                                             (C) 4, 2, 1, 3

17. The      correct        order   of   chromatin           (D) 2, 1, 4, 3
      organization from the following is

        I. Nucleosome                                    19. According to ICBN Rules the suffix of
       II. Solenoid
                                                            family name ends with “aceae”, whereas
       III. Double stranded DNA
                                                            prefix refers to
      IV. Chromosome

                                                             (A) Specific epithet
      Choose the correct sequence

       (A) I, IV, II, III                                    (B) Characteristic feature of the family

       (B) III, I, II, IV
                                                             (C) Generic epithet
      (C) I, II, III, IV
                                                             (D) Specific character of basic species
      (D) III, IV, I, II

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                                                      21. Assertion (A) : Apospory is not uncommon
20. Pick up the correct combination of the
      following using valid name and part used                             in some ferns like Pteris

      (A) Millets-Sorghum vulgare - Poaceae-
                                                          Reason (R) : In ferns some times the
          caryopsis
          Pulses-Cajanus cajan-Fabaceae-                                   prothallus is formed from
          Cotyledons                                                       vegetative      parts   of
          Fibers-Gossypiumherbaceum-
                                                                           sporophytic plant
          Malvaceae-Epidermal hairs of seed
          Fruit-Mangifera indica-Anacardiaceae-            (A) Both A and R are true, R is the
          Epicarp and Mesocarp of drupe                        correct explanation of A
      (B) Millets-Sorghum vulgare - Poaceae-
          Caryopsis                                        (B) Both A and R are true, but R is not
          Pulses-Cajanus cajanus-Fabaceae-                     the correct explanation of A
          Cotyledons
                                                           (C) Both A and R are not true
          Fibers-Gossypium herbaceum-
          Malvaceae-Epidermal hairs of seed                (D) A is true, but R is false
          Fruit-Mangifera indica-Anacardiaceae-
          Epicarp and Mesocarp of drupe               22. This biosphere reserve is recently notified
      (C) Millets-Sorghum vulgare - Poaceae-
                                                          by the Government of India
          Caryopsis
          Pulses-Cajanus cajan-Fabaceae-                   (A) Valley of Flowers
          Cotyledons
                                                           (B) Nanda Devi
          Fibers-Gossypiumherbaceum-
          Malvaceae-Epidermal hairs of fruit               (C) Nallamalais
          Fruit-Mangifera indica-Anacardiaceae-
          Epicarp and Mesocarp of drupe                    (D) Seshachalam
      (D) Millets – Sorghum vulgare - Poaceae-
          Caryopsis                                   23. Epiphytes are rare in Delhi because it has
          Pulses-Cajanus cajan-Fabaceae-                   (A) Moist climate
          Cotyledons
          Fibers-Gossypiumherbaceum-                       (B) Semi-arid climate
          Malvaceae-Epidermal hairs of seed                (C) Large amount of factories
          Fruit-Mangifera indica-Anacardiaceae-
                                                           (D) Large number of automobiles
          Mesocarp and endocarp of drupe

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24. Arrange the following in progressive                26. Pick up the sources of air pollution from

      manner with special reference to                      the following :

      ecological succession in xerosere                       I. Volcanic eruptions

        I. Funaria                                           II. Dust storms

       II. Rhizocarpon                                       III. Domestic sewage

                                                            IV. Pulp mills
       III. Poa
                                                             V. CFMs
      IV. Trees
                                                             (A) I, II and III
      (A) I, II, III, IV
                                                             (B) I, II, III and V
      (B) II, I, IV, III
                                                             (C) II, IV and V
      (C) II, I, III, IV
                                                             (D) I, II and V
      (D) I, III, II, IV
                                                        27. Which of the following has more redox
25. Match the following :                                   potential (E0) value ?

1. Aquatic habitats               I. Sciophytes              (A) Flavo proteins

2. Community in abundant light   II. Xerophytes              (B) Cytochrome B

3. Community in shade            III. Heliophytes            (C) Nicotinamide adenine dinucleotide

4. Community in dry conditions IV. Mesophytes                (D) Ubiquinone

                                 V. Hydrophytes
                                                        28. Respiratory quotient (R.Q) value of a
                  1   2     3     4                         simple sugar is

      (A)         V   III   I     II                         (A) Zero

      (B)         V   IV    I     II                         (B) More than one

      (C)         V   III   II     I                         (C) Less than one

      (D)         V   II    I     III                        (D) Equal to one


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29. Given below are two statements, one                        31. Which one of the following combination

      labeled as Assertion (A), and the other                     or chromosome number (N) and DNA
      labeled as Reason (R)                                       content (C) is true of the diplotene stage

      Assertion (A) : The pronounced decrease                     of mammalian oocytes ?
                            in quantum yield at red
                                                                   (A) 1N & 2C           (B) 2N & 4C
                            zone (greater than 680 nm)
                            is termed as red drop. It is           (C) 2N & 2C          (D) 1N & 4C
                            also known as Emerson’s
                            effect.                            32. Assertion (A) : As polyspermy is being

      Reason (R) : Discovery of Emerson’s                                          slowly    blocked,     the
                            effect has clearly shown                               cortical granules explode
                            the existence of two
                                                                                   and release their contents
                            photosystems.
      In the context of the above two statements                                   into the perivitelline
      which one of the following is correct ?                                      space.
      Codes :
       (A) A is correct but R is wrong                            Reason (R)     : Quick     blocking        of
       (B) A is wrong but R is correct                                             polyspermy      sets      in
      (C) A is correct, R is also correct
                                                                                   depolarization of the egg
      (D) A is wrong, R is also wrong
                                                                                   plasmalemma            and
30. Arrange the following compounds in order
                                                                                   mobilization of Ca2+ from
      in which they appear in Krebs cycle. Use
      the code given below.                                                        stores with in the egg.

        I. Succinic acid                                           (A) Both A and R are true and R is the
       II. Fumaric acid                                                correct explanation of A
       III. Oxaloacetic acid
                                                                   (B) Both A and R are true but R is not
      IV. Malic acid
                                                                       the correct explanation of A
      Code :
                                                                   (C) A is true but R is false
       (A) III, IV, II, I         (B) I, II, IV, III
      (C) II, III, I, IV          (D) I, III, II, IV               (D) Both A and R are false

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33. During early human brain development                       35. The order of evolutionary pattern of
      primary vesicles listed in List I gives rise
                                                                  nitrogen excretion in animals is as follows
      to derivatives in List II
                                                                   (A) Urea, Uric acid, Ammonia
               List I                     List II
                                                                   (B) Ammonia, Uric acid, Urea
        I. Telencephalon               1. Mid brain

       II. Mesencephalon               2. Optic vesicle            (C) Urea, Ammonia, Uric acid

      III. Diencephalon                3. Cerebellum               (D) Ammonia, Urea, Uric acid

      IV. Myelencephalon               4. Hippocampus
                                                               36. Mammalian heterodonty is expressed by

      Code :                                                      a dental formula. Match the dental formula
                 I      II   III   IV
                                                                  to the organism
       (A)      4       1    2     3
                                                                            List I                      List II
       (B)      2       1    3     4

       (C)      4       2    1     3                                      0, 0, 3, 3
                                                                     I.              = 32             1. Rabbit
                                                                          3, 1, 3, 3
       (D)      3       2    1     4
                                                                          2, 0, 3, 3
                                                                    II.              = 28             2. Man
34. During neural tube formation in the chick                             1, 0, 2, 3

      embryo the neural plate involves following                          1, 0, 2, 3
                                                                   III.              = 22             3. Sheep
      events in sequences                                                 1, 0, 1, 3

       (A) Shaping, convergence, folding,                                 2, 1, 2, 3
                                                                   IV.               = 32             4. Squirrel
             elevation, clockwise                                         2, 1, 2, 3

       (B) Convergence, elevation, folding,                                    I     II     III   IV
             shaping, clockwise
                                                                   (A)         3     1      4     2
       (C) Shaping,          folding,       elevation,
                                                                   (B)         2     1      3     4
             convergence, clockwise

       (D) Convergence, shaping, elevation,                        (C)         1     4      2     3

             folding, clockwise                                    (D)         4     1      2     3

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37. Assertion (A) : Absorption          of       the        38. The Bohr effect represents an interaction

                      products of carbohydrates                 between

                                                                 (A) O 2 equilibrium        and    Electron
                      and protein digestion are
                                                                      dissociation of Hb
                      against a concentration
                                                                 (B) O       equilibrium    and     Proton
                                                                         2
                      gradient, whereas the
                                                                      dissociation of Hb
                      absorption of the products
                                                                 (C) CO 2 equilibrium and Electron
                      of lipids are different.                        dissociation of Hb

                                                                 (D) CO 2     equilibrium    and    Proton
      Reason (R)    : The end products of
                                                                      dissociation of Hb
                      carbohydrates, proteins
                                                            39. Which one of the following chromosome
                      are absorbed into the
                                                                combinations is expected in an offspring
                      epithelial cells of intestine
                                                                obtained after selfing a plant having
                      is by active transport,                   AA BB CC DD homologous pairs ?

                      whereas the products of                     I. AA

                      lipids are by diffusion.                    II. BB

                                                                 III. CC
      In the context of the above two statements
                                                                IV. DD
      which one of the following is correct
                                                                The correct sequence of the above is
       (A) A is correct but R is wrong
                                                                 (A) I, III, II and IV
       (B) Both A and R are correct
                                                                 (B) I, II, III and IV

      (C) A is wrong but R is correct                            (C) I, IV, III and II

      (D) Both A and R are wrong                                 (D) I, III, IV and II

II}                                                    11                                          A-09-02
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40. Match the most commonly detected blood-                42. Sex linked genes on the entire
      group systems with probable number of
      their alleles                                           X-chromosome        of      Drosophila

               List I                       List II           melanogaster mapped and found to have
             Blood Group                    Alleles
                                                              a length of
       I. ABo                           1 20+
       II. MNSc                         2    5                 (A) 78 map units
                                                 +
      III. P                            3 30
                                                               (B) 68 map units
      IV. Rh                            4    4
                  I     II   III   IV                          (C) 80 map units
       (A)       2      1    4     3
                                                               (D) 82 map units
       (B)       1      2    3     4
      (C)        4      3    2     1
                                                           43. What are the two theories that are
      (D)        3      4    2     1
                                                              combined in the synthetic theory of
41. Assertion (A) : Gene is a biological entity-
                    a heritable function                      evolution ?
                    detected by observing the
                    effect of a mutation. A gene               (A) Darwin’s theory of natural selection
                    consists of all the DNA
                                                                   and Lamarck’s theory of use and
                    sequences necessary to
                    produce a single peptide                       disuse
                    or RNA product.
                                                               (B) Mendel’s theory of heredity and
      Reason (R)         : The gene is single,
                           contiguous       protein                Heckel’s theory of ontogeny repeats
                           encoding stretch of DNA.
                                                                   phylogeny
      In the context of the above two statements,
                                                               (C) Darwin’s theory of natural selection
      which one of the following is correct ?
       (A) Both A and R are true and R is                          and Mendel’s theory of heredity
           correct explanation of A
       (B) Both A and R are true but R is not                  (D) Lamarck’s theory of use and disuse
           the correct explanation of A
                                                                   and Heckel’s theory of ontogeny
      (C) A is true but R is false
      (D) Both A and R are false                                   repeats phylogeny

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 44. Match the various types of isolating                               45. Arrange following fossils in a row leading

      mechanisms that prevent gene exchange                                 from more like reptiles to more like

      between population of related species of                              mammals

      organisms                                                               I. Pelycosauria

         List I                            List II                            II. Cyanodonta

                                                                             III. Therapsida
 I. Habitat Isolation         1. Populations are isolated by
                                                                             IV. Mammalia
                                   different and incompatible
                                                                             (A) I, II, III and IV
                                   behaviour
                                                                             (B) II, III, I and IV
II. Seasonal Isolation        2. Restricted by differences in
                                                                             (C) I, III, II and IV
                                   structure of reproductive
                                                                             (D) II, I, III and IV
                                   organs

                                                                        46. Assertion (A) : The finches beaks evolved
III. Ethological Isolation    3. Populations live in same
                                                                                               to be larger in times of food
                                   regions but occupy different
                                                                                               shortage and smaller in
                                   habitats
                                                                                               times of abundance.
IV. Mechanical Isolation      4. Population exist in the
                                                                            Reason (R)       : The food supply fluctuated
                                   same region but are
                                                                                               through time according to
                                   sexually          mature   at
                                                                                               weather.
                                   different times
                                                                             (A) Both A and R are true and R is the
                  I      II    III    IV
                                                                                  correct explanation
       (A)        1      3     4       2                                     (B) Both A and R are true, but R is not
       (B)        3      4     1       2                                          the correct explanation

       (C)        2      4     1       3                                     (C) A is true but R is false

       (D)        3      2     1       4                                     (D) A is false but R is true

II}                                                                13                                            A-09-02
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Q.No. 47–50                                            lagging strand DNA fragments are primed


Read the passage below, and answer the                 by a short RNA primer molecules that are


questions that follow based on your                    subsequently erased and replaced with

understanding of the passage.                          DNA.

DNA replication takes place at a ‘Y’-shaped
                                                       DNA replication requires the cooperation of
structure called a replication fork. A self
                                                       many proteins. These include
correcting DNA polymerase enzyme
                                                        i. DNA polymerase and DNA primase to
catalyzes nucleotide polymerization in a

                                                          catalyze     nucleotide     triphosphate
5′ -to- 3′ direction, copying a DNA template

strand with remarkable fidelity. Since the two            polymerization;

strands of a DNA double helix are                       ii. DNA helicases and single strand DNA-

antiparallel, this 5′ -to- 3′ DNA synthesis can
                                                          binding (SSB) proteins to help in opening
take place continuously on only one of the
                                                          up DNA helix so that it can be copied ;
strands at a replication fork (the leading
                                                       iii. DNA ligase and an enzyme that degrades
strand). On the lagging strand, short DNA

                                                          RNA primers to seal together the
fragments must be made by a ‘backstiching’

process. Because the self correcting DNA                  discontinuously synthesized lagging-

polymerase cannot start a new chain, these                strand DNA fragments; and

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iv. DNA topoisomerases to help to relieve                 49. Which one of the following four statements

                                                              is incorrect ?
      helical winding and DNA tangling
                                                               (A) Leading strand is synthesized in
      problems. Many of these proteins
                                                                   5′ → 3′ direction

      associate with each other at a replication               (B) Lagging strand is synthesized by

      fork to form a highly efficient ‘replication                 ‘backstitching’ process

                                                               (C) DNA polymerase can directly
      machine’, through which the activities and
                                                                   synthesize new chain of DNA
      spatial movements of the individual
                                                               (D) Antiparallel strands of DNA are
      components are coordinated.                                  separated by helicases


47. Helical winding of DNA is removed by an               50. Which one of the following four statements

      enzyme                                                  is correct ?

       (A) DNA polymerase                                      (A) Leading strands is synthesized in
       (B) DNA primase                                             fragments
       (C) DNA helicase
                                                               (B) DNA fragments synthesis is initiated
       (D) DNA topoisomerase
                                                                   by DNA primer

48. Discontinually synthesized lagging strand                  (C) Leading and lagging strands are
      DNA fragments are sealed by which one                        synthesized in different manner
      of the following enzyme ?
                                                                   because the DNA strands are
       (A) RNA primase
                                                                   antiparallel
       (B) DNA ligase
                                                               (D) DNA polymerase alone coordinates
       (C) Single strand binding proteins
                                                                   replication of DNA process
       (D) DNA polymerase

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      Space for Rough Work




II}            16              A-09-02
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Source: Telangana State Eligibility Test. Question paper published by Telangana State Eligibility Test.