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Vaccines and Immunotherapy Questions and Answers

1.

Covishield is a :

Exam Year(s)

MH SET - 2025, SET Exam - 2025,

Answer: C

Covishield is a recombinant vector vaccine.

Covishield is the Serum Institute of India's version of the Oxford-AstraZeneca vaccine (ChAdOx1 nCoV-19). It uses a replication-deficient chimpanzee adenovirus as a vector carrying the gene for the SARS-CoV-2 spike protein, which the recipient's cells then make, triggering immunity.

It is not a DNA vaccine, which injects plasmid DNA directly (India's ZyCoV-D is one). Nor is it an attenuated vaccine: it contains no weakened coronavirus, chemically or otherwise, and the adenovirus vector cannot replicate.

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