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Phylogenetic Analysis Questions and Answers

1.

Which one of the following is a distance based method of tree construction ?

Exam Year(s)

MH SET - 2019, SET Exam - 2019,

Answer: A

The distance-based method is UPGMA.

UPGMA (unweighted pair group method with arithmetic mean) first converts sequences into a matrix of pairwise distances, then repeatedly joins the two closest taxa or clusters and recomputes average distances until one tree remains. Neighbour-joining is the other well-known distance method.

Maximum parsimony, maximum likelihood and Bayesian methods are character-based: they evaluate trees from the individual sites of the alignment, not from a summary distance matrix.

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